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Micafungin

  Cat. No.:  DC60080   Featured
Chemical Structure
235114-32-6
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More than 5000 active chemicals with high quality for research!
Field of application
Micafungin, also known as FK463, is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. It inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls. It received final approval from the U.S. Food and Drug Administration (FDA) on March 16, 2005. Micafungin works by way of concentration-dependent inhibition of 1,3-beta-D-glucan synthase resulting in reduced formation of 1,3-beta-D-glucan, which is an essential polysaccharide comprising one-third of the majority of Candida spp. cell walls. This decreased glucan production leads to osmotic instability and thus cellular lysis.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 235114-32-6
Chemical Name: Micafungin
SMILES: CCCCCOC1=CC=C(C2=CC(C3=CC=C(C(N[C@H]4C[C@H]([C@H](NC([C@@H]5[C@H]([C@H](CN5C([C@H]([C@@H](CC(N)=O)O)NC([C@H]([C@@H]([C@H](C6=CC(OS(=O)(O)=O)=C(O)C=C6)O)O)NC([C@@H]7C[C@H](CN7C([C@H]([C@H](O)C)NC4=O)=O)O)=O)=O)=O)C)O)=O)O)O)=O)C=C3)=NO2)C=C1
Formula: C56H71N9O23S
M.Wt: 1270.27
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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