AAN06119|cas 95906-11-9|DC Chemicals

Cas No.:	95906-11-9
Chemical Name:	Tris(2,4-di-tert-butylphenyl)phosphate
SMILES:	CC(C)(C)C1=CC(C(C)(C)C)=C(C=C1)OP(OC2=C(C=C(C=C2)C(C)(C)C)C(C)(C)C)(=O)OC3=C(C=C(C=C3)C(C)(C)C)C(C)(C)C
Formula:	C₄₂H₆₃O₄P
M.Wt:	662.92102
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A2 (sPLA2) through molecular docking[1].
Target:	sPLA2[1]
In Vivo:	Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP; 50 mg/kg and 70 mg/kg) exhibits significant anti-inflammatory activity in carrageenan induced paw odema model[1]. Tris(2,4-di-tert-butylphenyl)phosphate (50 mg/kg and 70 mg/kg) reduces the raw paw odema volume significantly[1].
References:	[1]. Vinuchakkaravarthy T, et al. Active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A(2) through molecular docking. Bioinformation. 2011;7(4):199-206.

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