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Difelikefalin HCl

  Cat. No.:  DC60186   Featured
Chemical Structure
2711717-77-8
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More than 5000 active chemicals with high quality for research!
Field of application
Difelikefalin is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin is selective for KOR over the μ-opioid receptor.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2711717-77-8
Chemical Name: 1-(D-phenylalanyl-D-phenylalanyl-D-leucyl-D-lysyl)-4-aminopiperidine-4-carboxylic acid trihydrochloride
Synonyms: Difelikefalin trihydrochloride; Difelikefalin hydrochloride; Difelikefalin HCl; CR845; CR 845; CR-845; FE 202845; FE202845; FE-202845;
SMILES: O=C(C1(N)CCN(C([C@@H](CCCCN)NC([C@@H](CC(C)C)NC([C@@H](CC2=CC=CC=C2)NC([C@@H](CC3=CC=CC=C3)N)=O)=O)=O)=O)CC1)O.[H]Cl.[H]Cl.[H]Cl
Formula: C36H56Cl3N7O6
M.Wt: 789.237
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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