EST73502|CAS 1838622-25-5|DC Chemicals

Cas No.:	1838622-25-5
Chemical Name:	(2R)-9-[2-(2,5-Difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Synonyms:	EST73502;FC1=C(CCN2CCC3(CN(C([C@H](O3)C)=O)CC)CC2)C=C(C=C1)F;(2R)-9-[2-(2,5-Difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
SMILES:	FC1C([H])=C([H])C(=C([H])C=1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C([H])([H])N(C([H])([H])C([H])([H])[H])C([C@@]([H])(C([H])([H])[H])O2)=O)C([H])([H])C1([H])[H])F
Formula:	C₁₉H₂₆F₂N₂O₂
M.Wt:	352.4188
Purity:	>98%
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

Cat. No.	Product name	Field of application
DC48169	DS34942424	DS34942424 is an orally potent analgesic without mu opioid receptor agonist activity.
DC42314	EST73502	EST73502 is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with Kis of 64 nM and 118 nM for MOR and σ1R, respectively. EST73502 has antinociceptive activity.
DC8626	Eluxadoline	Eluxadoline is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist.
DC9765	CERC-501(LY-2456302,Aticaprant)	CERC-501(LY-2456302) is a potent, selective antagonist of the kappa opioid receptor (KOR) (Ki = 0.81 nM vs. 24.0 nM and 155 nM for the μ-opioid receptor (MOR) and δ-opioid receptor (DOR), respectively.
DC7097	Cebranopadol(GRT-6005)	branopadol(GRT-6005) is a novel first in class compounds with potent agonist activity on ORL-1 (opioid receptor like -1) and the well established mu opioid receptor.
DC8298	BAN ORL 24	BAN ORL 24 is a potent, selective, competitive ORL1 non-peptide agonist. Displays 1000-fold selectivity over classical opioid receptors.