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FOY-251

  Cat. No.:  DC39025   Featured
Chemical Structure
71079-08-8
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More than 5000 active chemicals with high quality for research!
Field of application
FOY 251 is a metabolite of Camostat and a pollen protease inhibitor for prevention and control of allergy.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 71079-08-8
Chemical Name: 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic Acid
Synonyms: FOY251;FOY 251
SMILES: N/C(=N/C1=CC=C(C(OC2=CC=C(CC(=O)[O-])C=C2)=O)C=C1)/N
Formula: C16H14N3O4
M.Wt: 312.300063610077
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. K Beckh, et al. Elimination of the Low-Molecular Weight Proteinase Inhibitor Camostate (FOY 305) and Its Degradation Products by the Rat Liver. Res Exp Med (Berl). 1987;187(6):401-6. [2]. Ai Maekawa, et al. Camostat Mesilate Inhibits Prostasin Activity and Reduces Blood Pressure and Renal Injury in Salt-Sensitive Hypertension. J Hypertens . 2009 Jan;27(1):181-9.
Description: FOY 251 free base is an anti-proteolytic active metabolite camostate (HY-13512), acts as a proteinase inhibitor[1].
In Vitro: FOY 251 free base represents a dose-dependent inhibition of equivalent current in M-1 cells[2]. FOY-251 free base inhibits the proteolytic activity of prostasin[2].
References: [1]. K Beckh, et al. Elimination of the Low-Molecular Weight Proteinase Inhibitor Camostate (FOY 305) and Its Degradation Products by the Rat Liver. Res Exp Med (Berl). 1987;187(6):401-6.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC39025 FOY-251 FOY 251 is a metabolite of Camostat and a pollen protease inhibitor for prevention and control of allergy.
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