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GSK3685032

  Cat. No.:  DC58007   Featured
Chemical Structure
2170137-61-6
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More than 5000 active chemicals with high quality for research!
Field of application
GSK-3685032(GSK 3685032) is a first-in-class, potent, non-nucleoside, reversible, selective inhibitor of DNMT1 with IC50 of 0.036 μM. GSK3685032 induces robust loss of DNA methylation, transcriptional activation and cancer cell growth inhibition in vitro.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2170137-61-6
Chemical Name: GSK3685032 HCl
Synonyms: α-[[6-(4-Amino-1-piperidinyl)-3,5-dicyano-4-ethyl-2-pyridinyl]thio]benzeneacetamide;GSK3685032;GSK3685032 HCl;GTPL11750;BDBM491199;NSC837081;US10975056, Example 143
SMILES: S(C([H])(C(N([H])[H])=O)C1C([H])=C([H])C([H])=C([H])C=1[H])C1=C(C#N)C(C([H])([H])C([H])([H])[H])=C(C#N)C(=N1)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])N([H])[H]
Formula: C22H24N6Os
M.Wt: 420.5306
Purity: >98%
Sotrage: -20-4°C
MSDS
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MSDS_31165_DC58007
COA
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