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Isoxicam

  Cat. No.:  DC80001   Featured
Chemical Structure
34552-84-6
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More than 5000 active chemicals with high quality for research!
Field of application
Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis[1]. Isoxicam is a nonselective inhibitor of COX-1 and COX-2[2].
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 34552-84-6
Chemical Name: 2H-1,2-Benzothiazine-3-carboxamide,4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-, 1,1-dioxide
Synonyms: 2H-1,2-Benzothiazine-3-carboxamide,4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-, 1,1-dioxide;Isoxicam;4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,1-dioxo-1λ6,2-benzothiazine-3-carboxamide;4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,1-dioxo-1λ
SMILES: CC1=CC(=NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O)NO1
Formula: C14H13N3O5S
M.Wt: 335.33512
Purity: >98%
Sotrage: -20
Description: Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis[1]. Isoxicam is a nonselective inhibitor of COX-1 and COX-2[2].
Target: COX-1 COX-2
References: [1]. DiPasquale G, et al. The antiinflammatory properties of isoxicam (4-hydroxy-2methyl-N-(5-methyl-3isoxolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide). Agents Actions. 1975 Aug;5(3):256-63. [2]. Xu S, et al. Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network. J Biol Chem. 2014 Mar 7;289(10):6799-808.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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