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TH10785

  Cat. No.:  DC80020   Featured
Chemical Structure
1002801-51-5
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More than 5000 active chemicals with high quality for research!
Field of application
TH10785 is a small-molecule activator that binds to the active site of 8-oxo guanine DNA glycosylase 1 (OGG1) and enables the protein to completely cleave the damaged DNA strand, which results in an overall increased repair of oxidative DNA damage.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1002801-51-5
Chemical Name: TH10785
Synonyms: 4-Quinazolinamine, N-cyclohexyl-2-cyclopropyl-;TH10785
SMILES: N1=C2C(C=CC=C2)=C(NC2CCCCC2)N=C1C1CC1
Formula: C17H21N3
M.Wt: 267.37
Purity: >98%
Sotrage: -20
Publication: Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function-Science, 376 (6600), ?DOI: 10.1126/science.abf8980
Description: TH10785 is a small-molecule activator that binds to the active site of 8-oxo guanine DNA glycosylase 1 (OGG1) and enables the protein to completely cleave the damaged DNA strand, which results in an overall increased repair of oxidative DNA damage.
References: Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function-Science, 376 (6600), ?DOI: 10.1126/science.abf8980
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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