Cas No.: | 2173134-00-2 |
Chemical Name: | (2-((pyrazin-2-ylmethyl)amino)pyrimidin-5-yl)(8-oxa-2-azaspiro[4.5]decan-2-yl)methanone |
Synonyms: | Vanin-1-IN-1; Vanin-1IN-1; Vanin-1 IN-1; VUN34002; VUN-34002; VUN 34002 |
SMILES: | C1C2(CCOCC2)CN(C(C2C=NC(NCC3C=NC=CN=3)=NC=2)=O)C1 |
Formula: | C18H22N6O2 |
M.Wt: | 354.40 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Vanin-1-IN-1 is an inhibitor of vanin-1 enzyme which is a cell surface associated, giycosyiphosphatidyS inositol (GPi) anchored protein and plays an important role in metabolism and inflammation[1]. |
Target: | vanin-1 enzyme[1] |
References: | [1]. Agustin Casimiro-Garcia, et al. Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme. WO2018011681A1. |