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XP-59

  Cat. No.:  DC39053   Featured
Chemical Structure
890402-73-0
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Field of application
XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM[1].The SARS-CoV main proteinase (Mpro) plays a central role in the formation of the viral replicase/transcriptase complex and is thus an ideal target for the development of suitable dru
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 890402-73-0
Chemical Name: XP-59
Synonyms: XP-59 ;XP 59 ;XP59
SMILES: CN(C)C1=CC=C(C=C1)C(=O)ON2C3=CC=CC=C3N=N2
Formula: C15H14N4O2
M.Wt: 282.29
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM[1].
Target: Ki: 0.1 nM (SARS-CoV Mpro)[1].
In Vitro: The SARS-CoV main proteinase (Mpro) plays a central role in the formation of the viral replicase/transcriptase complex and is thus an ideal target for the development of suitable drugs[1].
References: [1]. Verschueren KH, et al,. A structural view of the inactivation of the SARS coronavirus main proteinase by benzotriazole esters. Chem Biol. 2008 Jun;15(6):597-606.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC39053 XP-59 XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM[1].The SARS-CoV main proteinase (Mpro) plays a central role in the formation of the viral replicase/transcriptase complex and is thus an ideal target for the development of suitable dru
DC39042 FGI-106 FGI-106 tetrahydrochloride is a potent and broad-spectrum inhibitor with inhibitory activity against multiple viruses. FGI-106 tetrahydrochloride is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 tetrahydrochloride also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 nM and 150 nM, respectively[1].FGI-106 is a potent compound for COVID-19 treament.
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