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Exicorilant

  Cat. No.:  DC70396  
Chemical Structure
1781244-77-6
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More than 5000 active chemicals with high quality for research!
Field of application
Exicorilant (CORT125281, CORT-125281) is a potent, selective glucocorticoid receptor (GR) antagonist, exhibits no cross-reactivity for the PR and AR receptors.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1781244-77-6
Chemical Name: Exicorilant
Synonyms: CORT125281;CORT-125281
SMILES: C([C@]12[C@@]([H])(CC3N(C4=CC=C(F)C=C4)N=CC=3C1)CCN(S(C1C=NN(C)N=1)(=O)=O)C2)(C1=NC=CC(C(F)(F)F)=C1)=O
Formula: C26H23F4N7O3S
M.Wt: 589.57
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC40890 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione is an intermediate of delta 9,11 steroids synthesis, for example, Vamorolone. The delta 9,11 steroids are modifications of glucocorticoids and has anti-inflammatory properties. The delta 9,11 steroids are agents for protection against cell damage (lipid peroxidation) and inhibition of neovascularization.
DC72900 HP210 HP210 is a selective glucocorticoid receptor modulator (SGRM). HP210 can inhibit the mRNA expression of IL-1β and IL-6. HP210 has the potential to study inflammation-related diseases.
DC71961 Nenocorilant Nenocorilant (Relacorilant) is a potent, orally activity glucocorticoid receptor (GR) antagonist with Ki value of 0.15 nM. Nenocorilant has pro-apoptotic effects and improves potency combined with cytotoxic agent. Nenocorilant can be used for cancer research.
DC71960 Beclometasone dipropionate monohydrate Beclometasone dipropionate monohydrate, the prodrug of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate monohydrate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate monohydrate can be used for asthma .
DC71054 Hydrocortisone aceponate Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid. Hydrocortisone aceponate can be used for various dermatoses research.
DC70396 Exicorilant Exicorilant (CORT125281, CORT-125281) is a potent, selective glucocorticoid receptor (GR) antagonist, exhibits no cross-reactivity for the PR and AR receptors.
DC50229 Glucocorticoids receptor agonist 3 Glucocorticoids receptor agonist 3 is a potent agonist of glucocorticoids receptor. Glucocorticoids receptor agonist 3 is useful to research diseases, such as obesity, diabetes, and inflammation (extracted from patent WO2000066522A1, compound 345).
DC50228 Cortodoxone-d2 Cortodoxone-d2 (11-Deoxycortisol-d2) is the deuterium labeled Cortodoxone. Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).
DC50227 Cortodoxone-d5 Cortodoxone-d5 (11-Deoxycortisol-d5) is the deuterium labeled Cortodoxone.
DC50226 Hydrocortisone-d3 Hydrocortisone-d3 (Cortisol-d3) is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
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