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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC46060 | Macarangioside D |
Macarangioside D, a megastigmane glucoside, possesses radical-scavenging activity.
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| DC46059 | Cr(III) protoporphyrin IX |
Cr(III) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.
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| DC46058 | L-Iduronic acid sodium salt |
L-Iduronic acid sodium salt is an important monosaccharide component of glycosaminoglycans (GAGs) such as Heparin, Heparan sulfate and Dermatan sulfate.
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| DC46057 | Mg(II) protoporphyrin IX |
Mg(II) protoporphyrin IX is a precursor of chlorophyll in Chlorella. Mg(II) protoporphyrin IX is a negative effector of nuclear photosynthetic gene expression. Mg(II) protoporphyrin IX can be used for the research of signaling molecule implicated in plastid-to-nucleus communication.
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| DC46056 | Cu(II) protoporphyrin IX |
Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair.
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| DC46055 | Ni(II) protoporphyrin IX |
Ni(II) protoporphyrin IX is a metalloporphyrin that has a low tendency toward axial ligation, becomes distorted when bound to ferrochelatase.
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| DC46054 | Pt(II) protoporphyrin IX |
Pt(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.
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| DC46053 | Cd(II) protoporphyrin IX |
Cd(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.
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| DC46052 | S-Adenosyl-L-methionine D3 |
S-Adenosyl-L-methionine D3 (S-Adenosyl methionine D3) is a deuterium labeled S-Adenosyl-L-methionine. S-Adenosyl-L-methionine is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor.
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| DC46051 | Zanubrutinib D5 |
Zanubrutinib D5 (BGB-3111 D5) is deuterium labeled Zanubrutinib. Zanubrutinib is a selective Bruton tyrosine kinase (Btk) inhibitor.
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| DC46050 | Lurbinectedin D3 |
Lurbinectedin D3 is deuterium labeled Lurbinectedin. Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively.
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| DC46049 | Ribociclib D6 hydrochloride |
Ribociclib D6 (LEE011 D6) hydrochloride is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.
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| DC46048 | Szechenyin A |
Szechenyin A is a constituent from Tibetan medicine Gentianae Szechenyii Spray.
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| DC46047 | Mal-PEG8-Val-Ala-PABC |
Mal-PEG8-Val-Ala-PABC is a cleavable Tesirine linker used in the synthesis of Tesirine, a drug-linker conjugate for ADC.
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| DC46046 | (3S,4S)-A2-32-01 |
(3S,4S)-A2-32-01 is a less active S-enantiomer of (3R,4R)-A2-32-01. (3R,4R)-A2-32-01 is an anti-virulence agent and a specific caseinolytic protein proteases (ClpP) inhibitor.
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| DC46045 | KA2507 hydrochloride |
KA2507 hydrochloride is a potent and highly selective inhibitor of HDAC6 (IC50=2.5 nM) with no significant toxicities. KA2507 hydrochloride shows antitumor efficacy and immune modulatory effects.
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| DC46043 | MRIA9 |
MRIA9 is an ATP-competitive, pan Salt-Inducible kinase (SIK) and PAK2/3 inhibitor, with IC50 values of 516 nM, 180 nM and 127 nM for SIK1, SIK2 and SIK3, respectively.
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| DC46042 | GSK040 |
GSK040 is a potent and highly selective BET BD2 inhibitor, with a pIC50 of 8.3. GSK040 shows more than 5000-fold selectivity for BET BD2 over BET BD1 (pIC50=4.6). GSK040 can be used for the research of oncology and immunology diseases.
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| DC46040 | Avasopasem manganese |
Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2*- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer.
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| DC46039 | YNT-185 |
YNT-185 is a nonpeptide, selective orexin type-2 receptor (OX2R) agonist, with EC50s of 0.028 and 2.75 μM for OX2R and OX1R, respectively. YNT-185 ameliorates narcolepsy-cataplexy symptoms in mouse models.
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| DC46036 | GX-201 |
GX-201 is a selective NaV1.7 inhibitor, with an IC50 of <3.2 nM for hNaV1.7.
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| DC46035 | Encainide |
Encainide (MJ9067) is an antiarrhythmic drug with class ⅠC activity. Encainide has the potential for life-threatening ventricular arrhythmias, symptomatic ventricular arrhythmias and supraventricular arrhythmias research.
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| DC46034 | ABR-238901 |
ABR-238901 is an orally active and potent S100A8/A9 blocker and inhibits S100A8/A9 interaction with its receptors RAGE (receptor for advanced glycation endproducts) and TLR4 (toll-like receptor 4). ABR-238901 has the potential for myocardial infarction (MI) research.
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| DC46033 | Miroestrol |
Miroestrol is a highly active phytoestrogen. Miroestrol can produce mammogenic effect. Miroestrol exhibits bone loss prevention and neuroprotective in ovariectomized mice. Miroestrol also can reduce cancer risk.
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| DC46032 | Antofloxacin hydrochloride |
Antofloxacin hydrochloride is a well tolerate, orally active and broad-spectrum 8-amino-fluoroquinolone with potent antibacterial activities. Antofloxacin hydrochloride shows superior antibacterial activity against gyrA mutation-positive H. pylori strains, especially in Asn87- mutated strains, compared to levofloxacin. Antofloxacin hydrochloride is a weak, reversible inhibitor of CYP1A2 for the treatment of infections caused by a diverse group of bacterial species.
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| DC46031 | Lucidin primeveroside |
Lucidin primeveroside (Lucidin 3-O-β-primeveroside) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. Lucidin primeveroside can be metabolically converted to genotoxic compound Lucidin, which subsequently forms lucidin-specific DNA adducts.
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| DC46029 | Yadanzioside L |
Yadanzioside L is a quassinoid and shows anti-tobacco mosaic virus (TMV) activity (IC50=4.86 μM).
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| DC46028 | Stachyose |
Stachyose, a small alkaloid, act as a hypoglycemic agent.
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| DC46027 | SDZ 224-015 |
SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1. SDZ 224-015 possesses anti-COVID-19 activity, targeting Mpro (IC50 of 30 nM).
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| DC46026 | Pratensein |
Pratensein, a flavonoid, ameliorates β-amyloid-induced cognitive impairment in rats via reducing oxidative damage and restoring synapse and BDNF levels.
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