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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC46025 Isorhamnetin 3,7-di-O-β-D-glucopyranoside
Isorhamnetin 3,7-di-O-β-D-glucopyranoside, a major flavonoid compound, is metabolized in vivo by intestinal bacteria to isorhamnetin and that isorhamnetin plays an important role as an antioxidant.
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DC46024 Isoflupredone
Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone can be used in wide range of conditions, such as infection and inflammatory diseases.
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DC46023 Corymbiferin
Corymbiferin is one of active constituents, responsible for anti-diabetic properties. Corymbiferin improves antioxidant capacity and carbohydrate metabolism in diabetic rats, along with the improvement of histopathology of livers and pancreatic β cells.
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DC46022 Ceftaroline fosamil inner salt
Ceftaroline fosamil (TAK-599) inner salt, a cephalosporin derivative, is an N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil inner salt can be used for the research of MRSA infection.
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DC46021 Benurestat
Benurestat is an orally active urease inhibitor. Benurestat can be used for infected ureolysis research.
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DC46020 7-Acetyllycopsamine
7-Acetyllycopsamine, a pyrrolizidine alkaloid, is a mild hepatotoxin. 7-Acetyllycopsamine can induce liver inflammation in mice.
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DC46019 Fengabine
Fengabine is a GABAergic antidepressant drug. Fengabine can be used for the research of depression.
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DC46018 Mn(II) protoporphyrin IX
Mn(II) protoporphyrin IX is a potential intravenous paramagnetic magnetic resonance contrast agent. Mn(II) protoporphyrin IX maintains strong paramagnetic properties.
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DC46017 Zenarestat
Zenarestat is a potent and orally active aldose reductase inhibitor. Zenarestat improves diabetic peripheral neuropathy in Zucker diabetic fatty rats.
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DC46016 Curcumin-β-D-glucuronide
Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer.
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DC46015 Pangelin
Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities.
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DC46014 CB2 receptor agonist 3
CB2 receptor agonist 3 is a robust and selective CB2 cannabinoid agonist with Kis of 7.6 and 900 nM for CB2 and CB1, respectively. CB2 receptor agonist 3 significantly increases P-ERK 1/2 expression in HL-60 cells.
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DC46013 BPK-21
BPK-21, an active acrylamide, suppresses T cell activation through blockade of ERCC3 function. BPK-21 specifically targets C342 in the helicase ERCC3.
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DC46012 Modified MMAF
Modified MMAF, an ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). Modified MMAF can be used for the targeted treatment of cancer.
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DC46011 Anticancer agent 9
Anticancer agent 9, a glycine derivative, is an anticancer agent. Anticancer agent 9 can inhibit tumor cells viability of myelogenous leukemia and human prostate cancer.
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DC46010 Sanguisorbigenin
Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA).
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DC46009 Rhaponticin 6′′-O-gallate
Rhaponticin 6′′-O-gallate is a stilbene glucoside gallate that can be found in rhizome of Rheum undulatum L. Rhaponticin 6′′-O-gallate inhibits nitric oxide production in lipopolysaccharide-activated macrophages.
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DC46008 Rhaponticin 2′′-O-gallate
Rhaponticin 2''-O-gallate, as a stilbene glucoside gallate, inhibits NO production.
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DC46007 Regaloside H
Regaloside H, a phenylpropanoid glycerol glucoside, is a gluconeogenesis inhibitor. Regaloside H can reduce glucose production in Hepatocytes.
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DC46005 Matairesinol monoglucoside
Matairesinol monoglucoside, a lignan compound, exhibits low activity on IFN-γ/STAT1 and IL-6/STAT3 signaling pathways with inhibition ratio of 5.8% and 7.0%, respectively.
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DC46004 Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside
Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside is an antioxidant with an IC50 of 26.6 μM (DPPH assay).
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DC46002 DMAPP
DMAPP (Dimethylallyl pyrophosphate) is an isoprenoid precursor. DMAPP, as an isomer of isopentenyl pyrophosphate (IPP), exists in virtually all life forms.
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DC46001 BPK-25
BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP.
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DC46000 PW0464
PW0464, a nanomolar potent complete G protein biased ligand, is a noncatechol D1R agonist, with an EC50 of 5.8 nM (Gs-cAMP).
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DC45999 SG3199-Val-Ala-PAB
SG3199-Val-Ala-PAB is an intermediate of Tesirine synthesis. Tesirine is a drug-linker conjugate for ADC which can be used for the research of several cancers.
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DC45998 Cassiaside B
Cassiaside B, a naphthopyrone, has potent antimicrobial activity.
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DC45997 Emodin-1-O-β-gentiobioside
Emodin-1-O-β-gentiobioside is an anthraquinone.
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DC45996 Gingerglycolipid A
Gingerglycolipid A is a monoacyldigalactosyl glycerol.
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DC45995 Manghaslin
Manghaslin is a flavonoid glycoside with anti-inflammatory activities. Manghaslin shows inhibitory activity against AChE with an IC50 of 94.92 µM.
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DC45994 Eupalinolide H
Eupalinolide H, a sesquiterpene lactone, has the potential to be used as natural anti-inflammatory agent.
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