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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC45640 κ-Carrageenan
κ-Carrageenan is a natural polymer which predominantly available in red seaweeds. κ-Carrageenan is an effective drug carrier to deliver curcumin in cancer cells and to induce apoptosis. κ-carrageenan serves as a potential inflammatory agent that magnifies existing intestinal inflammation.
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DC45639 SEluc-2
SEluc-2 is a small-molecule probe based on the firefly luciferin. SEluc-2, a bioluminescent probe for the sensitive and selective detection of thiols in living cells.
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DC45638 Cycloposine
Cycloposine is a steroidal alkaloid that can be found in the roots and rhizomes of Veratrum californicum. Cycloposine is also a teratogenic compound.
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DC45637 (+)-Syringaresinol
(+)-Syringaresinol, a lignan, is a NFAT transcription factor inhibitor, with an IC50 of 329.4 μM. (+)-Syringaresinol also can be used for the research of lymphocytic leukemia.
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DC45636 Imperialine 3-β-D-glucoside
Imperialine 3-β-D-glucoside is the glycoside of Imperialine. Imperialine 3-β-D-glucoside may exhibit anti-tumor properties against multi-drug resistant tumor cells.
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DC45635 Xanthiazone
Xanthiazone is a thiazinedione.
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DC45634 Xanthiside
Xanthiside (Xanthiazone O-β-D-glucoside) is a heterocyclic glucoside.
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DC45633 Kansuinine E
Kansuinine E is a plant-derived nitric oxide inhibitor (IC50=6.3 μM). Kansuinine E belongs to jatrophane-type diterpenoids and is isolated from the roots of E. kansui.
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DC45632 Theophyllol
Theophyllol (theophylline sodium acetate) can alter calcium levels in subcellular fractions of rat brain cortex.
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DC45630 Gel filtration medium G-100
Gel filtration medium G-100 is a gel filtration medium that can be used for protein purification.
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DC45625 XL388-C2-amide-PEG9-NH2 hydrochloride
XL388-C2-amide-PEG9-NH2 hydrochloride is an intermediate used in the synthesis of C26-linked Rapamycin analog.
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DC45624 Furosine dihydrochloride
Furosine dihydrochloride, an amino acid derivative, is an important chemical marker of early-stage Maillard reactions. Furosine dihydrochloride is closely related to a variety of diseases such as diabetes.
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DC45623 N-ε-propargyloxycarbonyl-L-lysine
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals.
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DC45622 3-Hydroxy furfural
3-Hydroxy furfural can be used for modulating the Saccharomyces cerevisiae and the Saccharomyces paradoxus.
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DC45621 PB2
PB2 is a tris(2-carboxyethyl)phosphine (TCEP) analogue increasing retinal ganglion (RGCs) cells survival after axotomy in vitro at nanomolar and picomolar concentrations. PB2 is substantially more permeable than TCEP. PB2, as a reducing agent, is highly neuroprotective for RGCs.
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DC45620 PB1
PB1 is a borane-protected TCEP (tris(2-carboxyethyl)phosphine) analogues. PB1 increases retinal ganglion cells survival after axotomy in vitro at nanomolar and picomolar concentrations. PB1 can be used for the research of neuroprotective.
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DC45619 α-(Methylamino)isobutyric acid
α-(Methylamino)isobutyric acid is a specific substrate for amino acid transport system A (ATA1). ATA mediate the uptake of short-chain neutral amino acids in a Na+-dependent manner.
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DC45618 L-2-Aminooxy-3-phenylpropanoic acid hydrobromide
L-2-Aminooxy-3-phenylpropanoic acid hydrobromide is a potent inhibitor of L-phenylalanine ammonia-lyase.
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DC45617 Glycyl-Exatecan D5 hydrochloride
Glycyl-Exatecan (D5 hydrochloride) is deuterium labeled Glycyl-Exatecan hydrochloride.
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DC45615 NOC-5
NOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors.
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DC45614 4-Methylumbelliferyl-α-D-galactopyranoside
4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA.
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DC45613 Ferroheme
Ferroheme, a complex of ferrous iron and a porphyrin, is an isosteric inhibitor of fatty acid binding to rat liver fatty acid binding protein.
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DC45612 GSK1820795A
GSK1820795A as a telmisartan analog is a selective antagonist at hGPR132a. GSK1820795A blocks activation of yeast cells expressing hGPR132a by N-acylamides.
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DC45610 Golgicide A-1
Golgicide A-1 (GCA-1) is a less active cis-diastereomer of Golgicide A (GCA). Golgicide A-1 weakly inhibits mosquito reproduction.
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DC45609 NH-3
NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment.
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DC45608 FK614
FK614 is an orally active, potent, selective PPARγ modulator (SPPARM). FK614 has different effects on the activation of PPARγ at each stage of adipocyte differentiation. FK614 is a nonthiazolidinedione insulin sensitizer. FK614 can be used for the research of hyperglycemia, hypertriglyceridemia, glucose intolerance and type 2 diabetes.
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DC45606 CLP-3094
CLP-3094 is a potent BF3 (binding function 3)-directed inhibitor of the androgen receptor (AR). CLP-3094 inhibits AR transcriptional activity (IC50=4 μM). CLP-3094 is a selective, potent GPR142 antagonist.
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DC45605 SN52
SN52 is a potent, competitive, and cell-permeable inhibitor of NF-κB2. SN52 is a variant of the SN50 peptide and inhibits the nuclear translocation of p52-RelB heterodimers. SN52 has a strong radiosensitization effect on prostate cancer cells. SN52 can be used for cancer research.
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DC45604 Ginger extract
Ginger extract exhibits anti-cancer, anti-inflammatory and chemotherapeutic effects in vivo.
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DC45603 Nasunin
Nasunin, an antioxidant anthocyanin, possesses antiangiogenic activity.
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