Selective dopamine agonist

Apoptosis inducer with selective antiproliferative activity.

Novel inhibitor of Ral binding to its effector RALBP1 and inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines

Novel selective Nav1.1 activator, increasing the firing activity of parvalbumin-expressing, fast-spiking GABAergic interneurons and increasing the spontaneous inhibitory post-synaptic currents (sIPSCs) recorded from pyramidal neurons

Novel HIF-1α prolyl hydroxylase inhibitor

Selective, orally active 5-HT6 antagonist

Functional Agonist of the Apelin (APJ) Receptor

A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor

Potent MTH1 inhibitor; RAS​/RAC-​mediated membrane ruffling inhibitor

Inducer of apoptosis

Novel potent inhibitor of protein kinase CK2

Potent and selective phospholipase D1inhibitor

An active opioid receptor antagonist

A second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor

Orally effective Fe chelator. being more active than desferrioxamine

A fluorescent, amyloid-specific dye. It binds at a different site than Pittsburgh Compound B and is a highly fluorescent marker for beta-sheet structures

A highly selective off-on fluorescent probe for imaging thioredoxin reductase in living cells, displaying a green fluorescence off-on change induced by the TrxR-mediated disulfide cleavage and subsequent intramolecular cyclization to liberate the masked n

Fluorescent analogue of the dopaminergic neurotoxin MPP+

Novel Fluorescent Probe of Blood-Brain Barrier Disruption in Animal Models

The first inorganic phosphate (Pi) targeted colorimetric and fluorescent probe to detect endogenous Pi in hemichannelclosed cells

Novel chemical probe for heterochromatin formation and function, disrupting of heterochromatin-mediated transcriptional gene silencing

Direct iron chelator from β(2) subunit of ribonucleotide reductase

Anti-fibrotic agent, acting as an adiponectin receptor (AdipoR) agonist

Potent and Highly Selective Inhibitors of GSK3b

Dopamine and the D1 receptor agonist, stimulating phosphoinositide hydrolysis

Analog of GSK199 inhibiting PAD4

Novel selective androgen receptor modulator, preventing body weight loss and sarcopenia in cancer cachexia models

The first highly potent and selective KDM5 inhibitor