Novel tubulin and HSP90 dual inhibitor, causing the destabilization of microtubules and degradation of HSP90 client proteins CRAF-1 and ERBB2, resulting in cell cycle arrest at the G2/M phase and apoptosis

Novel small molecule activator of PP2A (SMAP), negatively regulating c-myc in small cell lung cancer

Novel selective inhibitor of primordial germ cell (PGC) development, targeting poly(A)-tail-independent noncanonical translation (PAINT)

Isomer of KLH45 (AOB5741)

Novel Sirtuin-3 Inhibitor, Inhibiting Cell Survival and Proliferation, and Promoting Apoptosis of Head and Neck Cancer Cells

Novel Nur77 modulator, inducing apoptosis of cancer cells by activating the Nur77-Bcl-2 apoptotic pathway

First-in-class nudix hydrolase family inhibitor, potently and selectively engaging and inhibiting the MTH1 protein in cells

Clickable adenosine derivative, to capture newly polyadenylated transcripts, and next-generation sequencing reveals mRNA sequence motifs that are linked to polyadenylation

Standard for Ca2+ channel activativation

Mitochondrial permeability transition pore (PTP) inhibitor

Novel FKBP12 inhibitor

Highly ASKA- (analog-sensitive kinase alleles) selective inhibitor

This compound belongs to the class of chemical entities known as triterpenoids. These are terpene molecules containing six isoprene units.