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Home > Inhibitors & Agonists > Metabolic Enzyme/Protease

Metabolic Enzyme/Protease

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Cat. No. Product Name Field of Application Chemical Structure
DC76927 Arimistane
Arimistane is a metabolite of 7-oxo-DHEA and can be used as a diagnostic marker of 7-oxo-DHEA administration.Arimistane is a metabolite of 7-oxo-DHEA and can be used as a diagnostic marker of 7-oxo-DHEA administration.
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DC76926 Amiquinsin hydrochloride monohydrate
Amiquinsin hydrochloride monohydrate is a compound with hypotensive activity. Amiquinsin hydrochloride monohydrate is metabolized in vivo, and the major metabolite is 4-amino-6,7-dimethoxy-3-quinolinol hydrochloride hydrate.
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DC76925 Acremine F
Acremine F is a fungal metabolite that has been found in Acremonium.
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DC76924 8-Oxo-dATP lithium
8-Oxo-dATP lithium, as an oxidized purine nucleoside triphosphate, is hydrolyzed by MTH1 into monophosphates, thereby preventing errors caused by its misincorporation during DNA replication or transcription.
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DC76923 8-Bromo-2'-deoxy-ATP tetrasodium
8-Bromo-2'-deoxy-ATP (8-Bromo-dATP) tetrasodium is a derivative of the nucleoside triphosphate 2'-Deoxyadenosine-5'-triphosphate (dATP).
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DC76922 8-Aminoguanine
8-Aminoguanine is a endogenous purine. 8-Aminoguanine inhibits PNPase (purine nucleoside phosphorylase). 8-Aminoguanine induces diuresis/natriuresis/glucosuria.
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DC76921 6-Hydroxy bexarotene
6-Hydroxy bexarotene is the main circulating metabolite of bexarotene, found in rats, dogs, and humans. Compared to the parent compound, 6-hydroxy-bexarotene shows a significantly reduced ability to bind to retinoid receptors and exhibits very minimal activity in activating retinoic acid receptors.
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DC76920 5-Androstenetriol
5-Androstenetriol is a systemic radiation protector that can boost the host's immunity, leading to increased resistance to infections. 5-Androstenetriol can raise levels of IL-2, IL-3, and IFN, while countering the immunosuppressive effects of Hydrocortisone.
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DC76919 4-Hydroxyphenylpropionylglycine
4-Hydroxyphenylpropionylglycine is a metabolite of the conditionally essential amino acid Tyrosine.
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DC76918 3-Oxochenodeoxycholic acid
3-Oxochenodeoxycholic acid is an endogenous metabolite that can be found in feces. 3-Oxochenodeoxycholic acid can serve as an indicator for the diagnosis of certain diseases, such as COVID-19.
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DC76917 3-Methyl-2-butenal
3-Methyl-2-butenal (3-Methylbut-2-en-1-al) can be isolated from hops.
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DC76916 3-Hydroxylidocaine
3-Hydroxylidocaine is the major metabolite of Lidocaine in rats and sheep.
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DC76915 3-Epideoxycholic acid
3-Epideoxycholic acid is the microbial metabolite of Deoxycholic acid. 3-Epideoxycholic acid targets FXR of dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exhibits anti-inflammatory activity. 3-Epideoxycholic acid promotes the growth of bacteria Bacteroides.
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DC76914 3-cis-Hydroxyglibenclamide
3-cis-Hydroxyglibenclamide is the metabolism of Glibenclamid.
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DC76913 1-Monoarachidin
1-Monoarachidin is a fatty acid that is derived from 2-arachidonoylglycerol.
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DC76912 19(R)-Hydroxy prostaglandin F1α
19(R)-Hydroxy prostaglandin F1α is an ω-1 hydroxylase metabolite of PGF1α.
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DC76911 17(R)-Resolvin D1 methyl ester
17(R)-Resolvin D1 methyl ester is the methyl ester of Resolvin D1 (RvD1) induced by Aspirin with the 17R epimer (AT-RvD1). RvD is a regulator of transendothelial migration of human polymorphonuclear leukocytes and an anti-inflammatory agent. The 17R-trihydroxy-4Z of RvD1 also blocks transendothelial migration of human neutrophils (EC50 approximately 30 nM). AT-RvD1 is an effective form that protects against the rapid inactivation of Resolvin D1.
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DC76910 16-Carboxymitragynine
16-Carboxymitragynine is a metabolite of mitragynine.
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DC76909 15-keto Prostaglandin F1α
15-keto Prostaglandin F1α (15-keto PGF1α) is a prostaglandin F1α metabolite. 15-keto Prostaglandin F1α (15-keto PGF1α) is an effective substrate for PGR-2. 15-keto Prostaglandin F1α (15-keto PGF1α) can be used to study physiological processes such as prostaglandin metabolism and lipogenesis.
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DC76908 14,15-Leukotriene D4
14,15-Leukotriene D4 (14,15-LTD4) is a leukotriene that producted by eosinophils with Arachidonic acid that can be used as a negative control for the protein-protein inhibition activity of UNC6934.
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DC76907 13,14-Dihydro-15-keto-PGE2
13,14-Dihydro-15-keto-PGE2 participates in Bifidobacterium animalis F1-7 to alleviate opioid-induced constipation by 5-HT pathway.
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DC76906 1,3-Dipalmitoyl-2-stearoyl glycerol
1,3-Dipalmitoyl-2-stearoyl glycerol (1,3-Palmitin-2-stearin) is a triacylglycerol in which palmitic acid is located at the sn-1 and sn-3 positions, and stearic acid is at the sn-2 position. The levels of 1,3-Dipalmitoyl-2-stearoyl glycerol are associated with energy depletion caused by reduced food intake in rats.
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DC76905 1,3-Capryloyl-2-oleoylglycerol
1,3-Capryloyl-2-oleoylglycerol is a triglyceride. 1,3-Capryloyl-2-oleoylglycerol has its hydroxyl groups at the 1 and 3 positions of glycerol acylated by Caprylic acid and the hydroxyl group at the 2 position acylated by Oleic acid in its molecule.
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DC76904 1,2-Stearin-3-linolein
1,2-Stearin-3-linolein is a triacylglycerol. 1,2-Stearin-3-linolein has Stearic acid at sn-1 and sn-2 positions, and contains Linoleic acid at sn-3 position.
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DC76903 1,2,3-tri-γ-Linolenoyl glycerol
1,2,3-tri-γ-Linolenoyl glycerol is a triacylglycerol with γ-linolenic acid attached to the three esterification sites (1, 2 and 3) of glycerol.
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DC76902 (5α)-3,6-Dioxocholan-24-oic acid
(5α)-3,6-Dioxocholan-24-oic acid is a secondary bile acid.
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DC76901 (±)-Δ7-Mesembrenone
(±)-Δ7-Mesembrenone is a mesembrine-type alkaloid which can be extracted from various Sceletium.
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DC76900 (±)7(S),8(R)-EDT
(±)7(S),8(R)-EDT is an isomer of 7,8-EDT.
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DC76899 (+/-)-Adomeglivant
(+/-)-Adomeglivant ((+/-)-LY2409021) is a potent and selective glucagon receptor antagonist with hypoglycemic activity. (+/-)-Adomeglivant is effective in lowering blood sugar levels in both healthy people and people with type 2 diabetes. (+/-)-Adomeglivant is well tolerated by glucagon signaling blockade in patients with type 2 diabetes and significantly reduces fasting and postprandial blood glucose with a concomitant reversible elevation of aminotransferases. Glucagon signaling inhibition by (+/-)-Adomeglivant is a promising potential inhibitory approach for patients with type 2 diabetes and warrants further evaluation of its benefits and risks in longer clinical trials.
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DC76898 Piribedil N-oxide
Piribedil N-oxide is a metabolite of the dopamine receptor agonist Piribedil.
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