α-Amanitin, an 8-Aa cyclic peptide, is an selective inhibitor of RNA polymerase II and III.

α5IA is a selective inverse agonist for Α5 subtype of GABAA receptor with a higher intrinsic activity at the A5 subtype than other drugs.

α2β1 integrin-IN-15 highly potent, selective, allosteric small-molecule inhibitor of integrin α2β1 with IC50 of 12 nM.

ZYZ-488 is a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1), inhibits the activation of binding protein procaspase-9 and procaspase-3.

ZYTP1 is a novel, oral PARP inhibitor that inhibits PARP1, PARP2, Tankyrase-1 and Tankyrase-2 with IC50 of 5.4, 0.7, 133.3 and 289.8 nM, respectively.

ZXH-3-26 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC), shows activity exclusively on the BRD4 BD1 (DC50/5h=5 nM) and spares degradation of BRD2 or BRD3 in cellular degradation assays.

ZTM000990 is a small-molecule antagonist of the oncogenic Tcf4/β-catenin protein complex with IC50 of 0.64 uM.

ZT55 (JAK inhibitor ZT55) is a novel potent, highly-selective tyrosine kinase JAK2 inhibitor with IC50 of 31 nM.

ZST316 (ZST-316) is a small molecule DDAH1 (Dimethylarginine dimethylaminohydrolase 1) inhibitor with IC50 of 3 uM, Ki of 1 uM.

ZST152 (ZST-152) is a small molecule DDAH1 (Dimethylarginine dimethylaminohydrolase 1) inhibitor.

ZPCK (NSC 251810.

Zonampanel (YM 872) is a selective, potent and highly water-soluble, competitive AMPA receptor (AMPAR) antagonist with Ki of 96 nM.

Zofenopril Calcium(SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor.

ZM323881 a receptor tyrosine kinase inhibitor of VEGFR-2 (Flk-1), PDGFR-beta, EGFR, and FGFR1

ZM 323881 hydrochloride is a potent and selective inhibitor of human Flk-1 (vascular endothelial growth factor receptor 2, VEGFR-2/KDR) activity.

ZLN024 Hcl is a novel AMPK allosteric activator; activated α1β1γ1 and α2β1γ1 by around 2–2.5 fold with an EC50 of about 1–2 uM. IC50 value: 1-2 uM (EC50) [1] Target: AMPK activator ZLN024 activated AMPK in L6 myotubes and stimulated glucose uptake and

ZL0454 is a potent, highly selective small-molecule BRD4 inhibitor with IC50 of 49 and 32 nM for BRD4-BD1 and BRD4-BD2, respectively.

ZK261991 is a highly selective and potent VEGFR-kinase inhibitor, which is orally available.

ZK-216348 is a potent, selective, dissociated glucocorticoid receptor agonist with pIC50 of 7.7, shows selectivity over other nuclear hormone receptors..

ZK 200775 is a competitive GluR (AMPA)/kainate antagonist.

Zinterol (MJ 9184) is a potent and selective β2 adrenoceptor agonist with pKb of 8.3, displays >2 logs selectivity over β1 (pKb<5.7).

Zinterol (MJ 9184) is a potent and selective β2 adrenoceptor agonist with pKb of 8.3, displays >2 logs selectivity over β1 (pKb<5.7).

ZINC549719643 (ZINC 549719643) is a potent, non-covalent AmpC inhibitor with IC50 of 77 nM. .

ZINC-3573 racemate is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=3 uM), showing little activity against 315 other GPCRs and 97 representative kinases.

ZINC12427628 (Compound '628) is a potent, selective positive allosteric modulator of M2 mAChR with EC50 of 1.1 uM.

Z-Ile-Leu-aldehyde (Z-IL-CHO, GSI-XII, γ-Secretase inhibitor XII) is a potent gamma-secretase and Notch signaling inhibitor.

ZIKV inhibitor K22 is a small molecule that exerts a potent antiviral activity against a broad range of coronaviruses by targeting membrane-bound viral RNA replication, effectively inhibits ZIKV with IC50 of 2.1 uM

Zifaxaban is a novel, potent, selective, direct and oral factor Xa inhibitor with IC50 of 11.1 nM (human FXa), displays > 10,000-fold selectivity than other serine proteases.

Zicronapine is an antipsychotic agent that shows potent antagonistic effects at dopamine D1, D2 and serotonin 5HT2A receptors, exhibits monoaminergic activity and has a multi-receptorial profile..

ZGN-1061 (Aclimostat) is a novel potent, selective Methionine aminopeptidase 2 (MetAP2) inhibitor being investigated for treatment of diabetes and obesity.