Novel G9a (EHMT2) inhibitor, binding tightly inside the active site cavity of G9a, inhibiting the activity of G9a in both enzyme and cell based assays with much lesser toxicity than BIX-0129

Novel substrate-competive c-Src inhibitor

Novel modulator of PI3K and NF-κB activities, blocking migration and production of inflammatory mediators

Novel photoisomerizable potent and selective M1 ligand, mimicing the tricyclic chemical structure and display reversibly controlled activity, showing stronger inhibition upon illumination both in vitro and in cardiac atria ex vivo

Inhibitor of gene products associated with cell survival, proliferation, invasion, and angiogenesis, targeting NF-κB pathway, showing antiproliferative activity and unique mode of action

Novel water-soluble, potent, and selective TRPM8 receptor agonist

Novel TRPM8 agonist

Novel potent powerful lipid A analogue as a conjugation-ready TLR4 ligand

TLR4 antagonist, protecting against advanced diabetic nephropathy

Potent and selective CRTH2 antagonist

Potent and selective inhibitor of AKR1C3

Potent and selective inhibitor of AKR1C3

Novel potent and mycobacteria-specific antimycobacterial agent, targeting MmpL3, a mycobacterial mycolic acid transporterr, demonstrating MIC = 0.03, 2, and ≤ 0.12 μg/mL against Mabs, Mycobacterium avium complex (MAC), and Mtb respectively

Novel potent and mycobacteria-specific antimycobacterial agent, targeting MmpL3, improving the antimycobacterial activity and being also potent against Mtb

Novel potent, selective, and reversible inhibitor of human monoamine oxidase B (hMAO-B)

Novel potent, selective, and reversible inhibitor of human monoamine oxidase B (hMAO-B)

Selective dopaminergic reuptake inhibitor

Antineoplastic and Antibacterial; Inducer of death in cancer cells through a reactive oxygen species (ROS)-mediated mechanism; Dark blue cancer cell growth inhibitor

Natural antiangiogenic homoisoflavanone, inhibiting the proliferation, migration and tube formation ability of human retinal microvascular endothelial cells

Novel CREBBP Bromodomain Inhibitor

Novel potent and cell-permeable inhibitor of cAMP-response element binding protein (CREB)

Substrate for the assay of creatine kinase, providing a quick source of energy for muscle fibers to contract when they need an initial burst of energy

Foster Resonance Energy Transfer (FRET) pair for Aβ40 aggregates

Novel probe for selectively detecting sAβ species in Alzheimer's disease (AD)

Novel potent HDAC8 inhibitor

Novel NIR-II probe, noninvasively and dynamically visualizing and monitoring many physiological and pathological conditions of circulatory systems, including lymphatic drainage and routing, angiogenesis of tumor, and vascular deformity such as arterial th

Novel RORγt inhibitor, suppressing Th17 cell differentiation, reducing the severity of experimental autoimmune disease models such as EAU, EAE, and type 1 diabetes

Novel RORγt inhibitor, suppressing Th17 cell differentiation, reducing the severity of experimental autoimmune disease models such as EAU, EAE, and type 1 diabetes

Liposomal-encapsulated combination of daunorubicin and cytarabine for the treatment of newly diagnosed tAML or AML with myelodysplasia-related changes (AML-MRCs)

Novel potent and selective fluorescent inhibitor of glutaminase (GLS1)