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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC48444 | Palmitoleic acid-13C16 |
Palmitoleic acid-13C16 is the 13C labeled Palmitoleic acid. Palmitoleic acid, a composition of fatty acid, is implicated in the prevention of death from cerebrovascular disorders in SHRSP rats.
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| DC48443 | L-Tryptophan-13C11 |
L-Tryptophan-13C11 (Tryptophan-13C11) is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.
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| DC48442 | L-Tryptophan-13C11,15N2 |
L-Tryptophan-13C11,15N2 (Tryptophan-13C11,15N2) is the 13C- and 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.
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| DC48441 | Poly-L-lysine hydrobromide |
Poly-L-lysine (hydrochloride) is a water-soluble synthetic polypeptide.
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| DC48440 | m-PEGn-NHS ester |
m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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| DC48438 | Upamostat (WX-671) |
Upamostat (WX-671), a novel serine protease urokinase (uPA) inhibitor by inhibiting the urokinase-type plasminogen activator (uPA) system.
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| DC48437 | Methyl methanesulfonate |
Methyl methanesulfonate (MMS), a DNA alkylating agent, modifies both guanine (to 7-methylguanine) and adenine (to 3-methlyladenine) to cause base mispairing and replication blocks, respectively.
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| DC48436 | Merbromin |
Merbromin (Mercury dibromofluorescein disodium salt, Mercurochrome, Merbromine, Mercurocol, Sodium mercurescein, Asceptichrome, Supercrome, Brocasept, Cinfacromin), a xanthene dye, is a topical antiseptic used for minor cuts and scrapes. Merbromin is an organomercuric disodium salt compound and a fluorescein. Merbromin is a selective inhibitor of 3CLpro and provides a scaffold to design effective inhibitors of SARS-CoV-2.
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| DC48435 | Borofalan (10B) |
Borofalan (10B) (SPM-011; Steboronine), a Ionising radiation emitter, can be used to treat the head and neck cancer.
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| DC48433 | 4SC-203 (SC71710) |
4SC-203 (SC71710) is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs).
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| DC48432 | tert-Butyl 11-aminoundecanoate |
tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker that refers to the PEG composition. tert-Butyl 11-aminoundecanoate is applicable to the synthesis of a series of PROTACs.
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| DC48431 | ODM-207 |
ODM-207 is a potent and selective BET inhibitor that is structurally unrelated to the benzodiazepine. ODM-207 also shows potent antiproliferative effects in patient-derived cancer cells and in xenograft models.
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| DC48430 | gp91ds-tat |
gp91ds-tat, a peptide inhibitor for NADPH oxidase assembly, is composed of gp91phox sequence linked to the human immunodeficiency virus-tat peptide. The tat sequence facilitates the entry of this peptide into cells.
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| DC48429 | Di(N-succinimidyl) adipate |
Di(N-succinimidyl) adipate (DSAP) is an alkyl chain-based PROTAC linker that is applicable to the synthesis of PROTACs.
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| DC48428 | BM213 |
BM213, a potent and selective agonist for C5aR1, shows antitumor activity in a mouse model of mammary carcinoma.
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| DC48427 | BC-LI-0186 |
BC-LI-0186 is a selective blocker of Leucyl-tRNA synthetase (LRS, LeuRS) and Ras-related GTP-binding protein D (RagD) interaction (LRS-RagD interaction) (IC50 = 46.11 nM) by competing against RagD for LRS VC domain binding (KD = 42.1 nM), thereby inhibiting lysosomal localization of LRS and mTORC1 activity. It also effectively suppresses the activity of cancer-associated mTOR mutants and the growth of rapamycin-resistant cancer cells.
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| DC11044 | Omidenepag Isopropyl Featured |
Omidenepag Isopropyl (DE-117, OMDI) is the prodrug of Omidenepag, which is a potent, selective agonist human EP2 receptor; demonstrates excellent IOP-lowering activities following ocular administration in ocular normotensive monkeys, Omidenepag Isopropyl (OMDI) is a clinical candidate for the treatment of glaucoma.
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| DC20466 | MsbA inhibitor 1 Featured |
MsbA inhibitor 1 is a novel small molecule lipopolysaccharide biogenesis inhibitor, inhibits MsbA, an ATP-dependent flippase that translocates LPS across the inner membrane; causes mislocalization of LPS to the cell interior, inhibits Δ5 strain with MIC o
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| DC26112 | SLMP53-1 Featured |
SLMP53-1 is a novel reactivator of wild-type and mutant p53, shows a p53-dependent anti-proliferative activity in human wt and mut p53R280K-expressing tumor cells.
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| DC20571 | TRIF agonist AV-C Featured |
TRIF agonist AV-C is a novel TRIF pathway agonist that activates innate and interferon-associated responses, strongly inhibits replication of ZIKV, CHIKV, and DENV (IC90~5 uM).
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| DC28336 | Se-Methylselenocysteine Featured |
Se-Methylselenocysteine, a precursor of Methylselenol, has potent cancer chemopreventive activity and anti-oxidant activity. Se-Methylselenocysteine is orally bioavailable, and induces apoptosis.
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| DC20890 | ChoK-α inhibitor CK37 Featured |
A potent, specific, competitive inhibitor of choline kinase-α (Chok-α) by targeting the choline binding site; significantly increases LC3II expression in MCF-7 and MCF-7/TAM cells, increases the size and number of autophagosome, causes MCF-7 and MCF-7/TAM
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| DC22930 | PF-4878691 (3M-852A) Featured |
PF 04878691 (PF 4878691, S 32865, 852A, 3M 001) is a selective TLR7 agonist that potently induces IFN-α and IFN-regulated proteins from human PBMC.
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| DC20076 | GPR4 antagonist 3(NE 52-QQ57 ) Featured |
GPR4 antagonist 3 is a selective, and orally available GPR4 antagonist with an IC50 of 70 nM. Anti-inflammatory activities.
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| DC21240 | LLY-283 Featured |
LLY-283 (LLY283) is a potent, selective inhibitor of arginine methyltransferase 5 (PRMT5) with IC50 of 22 nM.
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| DC8506 | S-99 Featured |
S-99 inhibits LPS-induced TNFa release assay in vivo
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| DC8528 | RO495 Featured |
RO495 is a very potent TYK2 inhibitor with a IC50 of 1.5nM on TYK2 as tested in cell-based pharmacological assays
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| DC8525 | NIBR-17 Featured |
NIBR-17 is a pan class I PI3K inhibitor with IC50 values of 1, 9.2, 9 and 20 nM respectively for PI3Kapha - delta.
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| DC8502 | GNE-490 Featured |
GNE-490 is a highly selective pan-PI3K inhibitor and demonstrates selectivity over mTOR.
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| DC8519 | GDC046 Featured |
GDC046 is a potent lead analog with good kinase selectivity, physicochemical properties, and pharmacokinetic profile.
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