N-Dodecanoyl-L-homoserine lactone-3-hydrazone-biotin (N-Dodecanoyl-L-hsl-3-hydrazone-biotin) is a biotin-tagged bacterial quorum sensing probe that links the quorum sensing signaling molecule AHL (acyl-homoserine lactone) to biotin via a hydrazone bond.

Org 6582 is a competitive, selective, and long-acting 5-HT (Ki = 89 nM) uptake inhibitor. Org 6582’s inhibitory effect on 5-HT uptake can last for more than 48 hours. Org 6582 can be used for research on depressive disorders.

D-CS319 is a potent inhibitor of metallo-𝛽-lactamases (MBLs) with IC50 values of 2.0 and 3.0 μM for IMP-1 and IMP-78, respectively. D-CS319 has antibacterial activity.

ADEP-14 is a bacterial ClpP activator with EC50s of 0.46 and 3.67  μM for Neisseria meningitides ClpP (NmClpP) and Escherichia coli ClpP (EcClpP). ADEP-14 binds to ClpP H sites and activates the protease. ADEP-14 has antibacterial activity. ADEP-14 can be used for bacterial infections research.

10-Butyl Ether Minocycline (BEM), a Minocycline derivative, is an MMP-8 and MMP-9 inhibitor with IC50s of 69.4 µM and 47.0 µM, respectively. 10-Butyl Ether Minocycline suppresses LPS-induced microglial activation. 10-Butyl Ether Minocycline inhibits VEGF-induced endothelial cell migration and L-Glutamine-induced ROS levels. 10-Butyl Ether Minocycline significantly reduces alcohol consumption in the Chronic Intermittent Ethanol (CIE) mouse model of alcohol dependence. 10-Butyl Ether Minocycline can be used for the study of neuroimmune-inflammatory diseases and Alcohol use disorder (AUD).

ALG-097558 is an orally active 3CLpro inhibitor. ALG-097558 demonstrates pan-coronavirus activity against various SARS-CoV-2 variants as well as other human coronaviruses (HCoVs) such as SARS-CoV-1, α-HCoV 229E, and β-HCoV OC43. ALG-097558 demonstrates potent inhibition with IC50s of 2 nM (SARS-CoV-2 3CLpro) and 6 nM (229E 3CLpro). ALG-097558 demonstrates antiviral activity in the SARS-CoV-2 hamster infection model. ALG-097558 can be used for the study of viral infections[1].

GPI2A is a 20-mer antisense oligonucleotide sequence that is complementary to a region of the HIV-1 gag gene. GPI2A shows a significant inhibitory effect on p55 and its cleavage product p39/41.

GPI2A sodium is a 20-mer antisense oligonucleotide sequence that is complementary to a region of the HIV-1 gag gene. GPI2A shows a significant inhibitory effect on p55 and its cleavage product p39/41.

GNKG168 is a synthetic, 21-mer, unmethylated CpG oligodeoxynucleotide. It acts as a TLR9 agonist with immunostimulatory activity.

GNKG168 sodium is a synthetic, 21-mer, unmethylated CpG oligodeoxynucleotide. It acts as a TLR9 agonist with immunostimulatory activity.

GD3 Ganglioside ammonium is a prominent ganglioside of human melanoma. GD3 Ganglioside ammonium is an inducer of mitochondrial permeability. GD3 ganglioside ammonium directly targets mitochondria in a bcl-2-controlled fashion. GD3 ganglioside ammonium is rapidly synthesized from accumulated ceramide after the clustering of death-inducing receptors and triggers apoptosis.

Gatuzosiran, a siRNA,is a 17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13) synthesis reducer. It is used for the study of fatty liver disease.

Gatuzosiran sodium, a siRNA,is a 17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13) synthesis reducer. It is used for the study of fatty liver disease.

Gataparsen is an antisense oligonucleotide directed against survivin mRNA with potential antitumor activity.

Gataparsen sodium is an antisense oligonucleotide directed against survivin mRNA with potential antitumor activity.

GalNac-siRNA negative control (21nt) is the negative control form of GalNac-siRNA. GalNac-siRNA is an Asialoglycoprotein receptor (ASGPR)-targeted inhibitor conjugate. GalNac-siRNA is promising for research of hereditary transthyretin amyloidosis, acute hepatic porphyria, hemophilia and hypercholesterolemia.

Etidaligide, an AsiDNA, a first-in-class DNA repair inhibitor designed to prevent the repair of DNA damage in tumour cells. It also activates DNA-dependent protein kinase (DNA-PK) and poly (ADP-ribose) polymerase enzymes that induce phosphorylation of H2A

Etidaligide sodium, an AsiDNA, a first-in-class DNA repair inhibitor designed to prevent the repair of DNA damage in tumour cells. It also activates DNA-dependent protein kinase (DNA-PK) and poly (ADP-ribose) polymerase enzymes that induce phosphorylation

Erisonersen, an antisense oligonucleotide, is a prion protein synthesis reducer. It is used for the study of Prion disease.

Erisonersen sodium, an antisense oligonucleotide, is a prion protein synthesis reducer. It is used for the study of Prion disease.

Edutirsen, an antisense oligonucleotide, is a 1-acylglycerol-3-phosphate O-acyltransferase (PNPLA3) synthesis reducer.

Edutirsen sodium, an antisense oligonucleotide, is a 1-acylglycerol-3-phosphate O-acyltransferase (PNPLA3) synthesis reducer.

Edifoligide is a decoy oligonucleotide that binds to and inhibits E2F transcription factors and thus may prevent neointimal hyperplasia and vein graft failure

Edifoligide sodium is a decoy oligonucleotide that binds to and inhibits E2F transcription factors and thus may prevent neointimal hyperplasia and vein graft failure

Ecad saRNA is a small activating RNA (saRNA) targeting the E-cadherin genes. Ecad saRNA induce expression of the E-cadherin genes, and targets the E-cadherin promoters at ?215 relative to gene's transcription start site.

dsP53-285 saRNA is a small activating RNA (saRNA) that readily activates wild-type p53 expression by targeting its promoter. dsP53-285 saRNA suppresses bladder cancer cells growth and metastasis.

DNMT1 aptamer sodium is a DNA aptamer for binding and inhibition of DNA methyltransferase 1 (DNMT1).

Diranersen, an antisense oligonucleotide, is a tau protein synthesis reducer. It is used for the study of Alzheimer's disease.

Diranersen sodium, an antisense oligonucleotide, is a tau protein synthesis reducer. It is used for the study of Alzheimer's disease.

Daplusiran is a siRNA in JNJ-3989 (JNJ-73763989). JNJ-3989 is comprised of 2 siRNAs (Daplusiran and Tomligisiran), that target hepatitis B virus (HBV) mRNAs for degradation, thereby inhibiting HBV replication.