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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC2086 | PF-670462 Featured |
PF 670462 is a selective casein kinase, CK1ε and CK1δ inhibitor which also shows potency against 42 other kinases.
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| DC12178 | Pemigatinib Featured |
Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma.
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| DC7550 | PBIT Featured |
PBIT is a potent, cell-permeable inhibitor of Jumonji histone demethylase (JHDM). Innhibits JARID1B (also known as KDM5B or PLU1) with an IC₅₀ of about 3 μm in vitro.
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| DC11445 | Parthenolide Featured |
Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium).
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| DC8459 | Palovarotene(R 667) Featured |
Palovarotene (R-667, RO-3300074) is a selective retinoic acid receptor gamma(RAR-γ) agonist for the treatment of emphysema.
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| DC8638 | Paclitaxel Featured |
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
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| DC7477 | pac-1 Featured |
PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3.
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| DC10798 | p38-α MAPK-IN-1 Featured |
p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.
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| DC25200 | PF-1355 Featured |
PF-1355 is a potent, selective, orally active Myeloperoxidase (MPO) inhibitor with EC50 of 1.47 uM.
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| DC32580 | MYCi975 Featured |
MYCi975, also known as NUCC-0200975, is a potent and selective MYC Inhibitor. MYCi975 disrupts MYC/MAX interaction, promotes MYC T58 phosphorylation and MYC degradation, and impairs MYC driven gene expression.
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| DC32374 | Nicotinamide Mononucleotide Featured |
Nicotinamide Mononucleotide, also known as ("NMN" and "β-NMN") is a nucleotide derived from ribose and nicotinamide Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinuc
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| DC26175 | NLX-101(F-15599) Featured |
NLX-101(F-15599) is a novel compound that activates serotonin 5-HT1A receptors with exceptional selectivity, having over 1000-fold higher affinity for this target over other receptors.
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| DC7221 | P22077 Featured |
P22077 is a potent inhibitor of ubiquitin-specific protease (USP) 7 (EC50=8.6 uM), P22077 also inhibits the closely related deubiquitinase (DUB) USP47.
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| DC5188 | Sarecycline(P005672 hydrochloride) Featured |
P005672 is a phase II drug for antibacterial/anti-inflammatory acne treatment.
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| DC7222 | P005091(P5091) Featured |
P005091(P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.
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| DC12312 | OTX008 (Calixarene 0118; PTX008) Featured |
OTX008 is a selective inhibitor of galectin-1.
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| DC5195 | Omecamtiv mecarbil (CK-1827452) Featured |
Omecamtivmecarbil (CK-1827452) is a specific cardiac myosinactivator and a clinical drug for left ventricular systolic heart failure.
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| DC10473 | NVS-PAK1-1 Featured |
NVS-PAK1-1 potently inhibits autophosphorylation of PAK1 (S144) at 0.25 µM in the Su86.86 cell line and MEK S289 phosphorylation with an IC50 = 0.21 in Su86.86 cells in which PAK2 is downregulated.
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| DC9769 | NVP-CGM097 (CGM-097) Featured |
NVP-CGM097 (CGM-097) is a potent and selective MDM2 inhibitor.
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| DC26035 | NUC-7738 Featured |
NUC-7738 is a phosphoramidate transformation of cordycepin (3’-deoxyadenosine; 3’-dA), a derivative of adenosine that was first isolated from Cordyceps sinensis.
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| DC5047 | NU7026 Featured |
NU7026 is a potent DNA-PK inhibitor with IC50 of 0.23 μM, 60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR.
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| DC7165 | NSI-189 Featured |
NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.
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| DC10484 | NSC781406 Featured |
NSC781406 is a highly potent PI3K and mTOR inhibitor with an IC50 of 2 nM for PI3Kα.
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| DC20228 | NSC617145(WRN inhibitor) Featured |
NSC617145 is a Werner syndrome helicase (WRN) helicase inhibitor (IC50 = 250 nM).
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| DC9641 | NSC348884 Featured |
NSC348884 is a nucleolar phosphoprotein that displays several biological activities in ribosome biogenesis, cell proliferation, cytoplasmic/nuclear shuttle transportation, nucleic acid binding, ribonucleic cleavage, and centrosome duplication.
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| DC8783 | NS 9283 Featured |
NS 9283 is a positive allosteric modulator of α4β2 receptor; increases the potency of Ach-evoked currents ~60 fold without effecting the maximum efficacy (HEK293-hα4β2 cells).
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| DC8398 | NPS-1034 Featured |
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.
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| DC4111 | Nolatrexed (AG-337) Featured |
Nolatrexed (AG-337), inhibits purified recombinant human thymidylate synthase (TS) with a Ki of 11 nM, and displays non-competitive inhibition kinetics. It was further shown to inhibit cell growth in a panel of cell lines of murine and human origin, displ
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| DC7212 | NMS-873 Featured |
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP).
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| DC5172 | NLG919(GDC-0919) Featured |
NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM.
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