Psoromic Acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase. Psoromic acid (PA) potently and selectively inhibits RabGGTase with an IC(50) of 1.3 μM. Mutation of (α)His dramatically enhances the reaction rate, indicating that the activity of RabGGTase is likely regulated in vivo. The covalent binding of PA to the N-terminus of the RabGGTase α subunit seems to potentiate its interaction with the active site and explains the selectivity of PA for RabGGTase. Psoromic acid provides a new starting point for the development of selective RabGGTase inhibitors.

Leucylalanine (Leu-Ala) is use to make non-electrolytic triorganotin(IV) derivatives (general formulae R3Sn(HL)) to study models of metal-protein interactions.

XRP44X is a potent Ras-Net (Elk-3) pathway inhibitor.

Decane, 1-methoxy- also known as Decyl Methyl Ether, it is a fatty ether used as a possible diesel fuel extender. It is aroma compound with a fresh scent.

Diisopropyl fumarate is used as scaffolds for bone tissue engineering.

BW245C has potent platelet anti-aggregating actions following parenteral or oral administration which makes this hydantoin a potentially-useful anti-thrombotic prostaglandin analogue.

Bromo-PEG6-bromide is a PEG derivative containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

Perthane is the diethyl derivative of common pesticide DDD. It may prevent the formation of spontaneous mammary carcinoma, and also may causes adrenocortical atrophy in humans.

DDE is also know as 4,4’-DDE. It is a metabolite of DDT (D434195), a synthetic organochlorine insecticide that functions by opening sodium ion channels in the insects’ neurons, causing them to fire spontaneously which in turn leads to death. 4,4’-DDE has shown to have endocrine disrupting effects on gonadotropin hormones in pituitary gonadotrope cells.

TDE is an Organochlorine insecticide that is slightly irritating to the skin.

Amino-PEG5-amine is a PEG derivative containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

Endrin is found in food products.

Amlodipine besilate impurity B is a biochemical.

Propargyl-PEG3-alcohol is a PEG derivative containing a hydroxyl group and a propargyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Biotin-PEG4-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. PEG Linkers may be useful in the development of antibody drug conjugates.

beta-Casomorphin 5 is an opioid receptor agonist, is a member of the β-casomorphin peptide family derived from β-casein. β-casomorphins are used to study their differential effects on processes such as hyperglycemia, oxidative stress, opioid signalling and immunosuppression.

[4-(Diethoxy-phosphorylamino)-butyl]-phosphoramidic acid diethyl ester is a PEG Linker.

Prednisolone valerate acetate is a derivative of Prednisolone, which is a synthetic corticosteroid, metabolically interconvertible with prednisone, and an impurity of Hydrocortisone. Prednisolone 21-Acetate Valerate is used in multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer.

NHS-LC-Biotin, or Succinimidyl 6-(biotinamido)hexanoate, is an amino-reactive biotinylation reagent with a long spacer arm which helps alleviate steric hindrance. NHS-LC-Biotin is used to biotinylate proteins, peptides, or amino acids by reacting with primary amines as found in the N-terminus and Lysine side chains.

Tetraethyl butane-1,4-diylbis(phosphonate) is a non-PEG crosslinker. Crosslinkers may be useful in the development of antibody drugconjugates.

Cyheptamide is an anticonvulsant.

alpha-Artemether is a Quinghaosu derivative which shows antimalarial and antifungal activity.

F-Chemotactic peptide is a potent chemoattractant for human neutrophils.

Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a.

Monactin is a Marcrotetrolide antibiotic produced by cycloheximide producing species of Streptomyces; it is homolog of nonactin from the same species.

Tilbroquinol is a quinoline-based antibiotics.

Amisulpride, (R)-, is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.

Bromosulfalein has been commonly used as both a substrate and inhibitor of organic anionic transporting polypeptide 1B1 (OATP1B1), OATP1B3, OATP1A2, and OATP2B1, as well as multidrug resistance protein 2 (MDR2). It has also been used for in vivo studies of liver and biliary system function and as an anionic dye for the quantitative estimation of protein levels in tissue homogenates or purified samples.

Chloramphenicol base is a bioactive chemical.

Digitoxin is a cardiac glycoside sometimes used in place of DIGOXIN. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting.