Phenol-d6 is a deuterated form of phenol. Phenol is a disinfectant preservative with a broad spectrum of antibacterial properties.

Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is a long-acting beta-lactam antibiotic effective against many bacterial infections such as impetigo.

Olomorasib (KRAS G12C inhibitor 19, LY3537982) is a potent and highly selective second-generation inhibitor of GDP-bound KRAS G12C, with the potential to treat patients with advanced solid tumors carrying the KRAS G12C mutation.

Amelenodor (NX-13) is an orally available, gut-selective molecule that activates the mitochondrial receptor NLRX1 to reduce intestinal inflammation. It promotes oxidative phosphorylation while suppressing proinflammatory pathways like Th1/Th17 differentiation and cytokine production. It has the potential to treat inflammatory bowel disease (IBD).

Nudifloramide (2PY, N-methyl-2-pyridone-5- carboxamide) is a pyridine derivative of nicotinamide that inhibits PARP-1 (poly (ADP-ribose) polymerase-1) activity in vitro, with an IC50 of 8 µM.

N-Boc-piperazine-d8 is the deuterated derivative of 1-t-Butoxycarbonylpiperazine.1-t-Butoxycarbonylpiperazine is a piperazine organic intermediate, which is often used to synthesize drug molecules with antiviral, antibacterial and other biological activities.

Morpholine-d8 Hydrochloride is the deuterated derivative of morpholin hydrochloride. Morpholine hydrochloride is an antiviral drug that works by inhibiting influenza virus, herpes virus, etc. Its synthesis involves morpholine derivatives as intermediates.

Monohydroxyaluminum diacetylsalicylate (Aluminum aspirin) is an aluminum salt of aspirin formed by the reaction of aluminum alcoholates with aspirin. It may exhibit anti-inflammatory, analgesic, and antipyretic effects, making it useful in non-steroid anti-inflammatory drugs (NSAIDs) research.

ID11916 is an orally available antagonist of Androgen receptor (AR) that blocks androgen binding, AR nuclear translocation, and transcriptional activity. It also inhibits PDE5 and exhibits anti-proliferative activity. ID11916 inhibits tumor growth in the MDA-MB-453 xenograft model.

EZH2/HSP90-IN-29 is a potent dual inhibitor of EZH2 and HSP90, with IC50s of 6.29 nM and 60.1 nM, for EZH2 and HSP90, respectively, that induces M-phase cell cycle arrest, promotes apoptosis/necrosis-related gene expression, and inhibits ROS catabolism. It crosses the blood-brain barrier and can show potential as a tractable anti-GBM agent for glioblastoma research.

Ethane-d4-1,2-diamine dihydrochloride is the deuterated form of 1,2-diaminoethane dihydrochloride.1,2-diaminoethane dihydrochloride is a laboratory reagent with protein cross-linking effect, mainly used in molecular modification or cell inhibition experiments in biochemical research.

EIPA hydrochloride (L593754 hydrochloride, MH 12-43 hydrochloride) is an orally active inhibitor of the TRPP3 channel with an IC50 of 10.5 μM. It also inhibits NHE3, affecting amino acid transport and autophagy regulation in intestinal epithelial cells.

D4-nicotinic acid is the deuterated form of nicotinic acid. Nicotinic Acid is a water-soluble vitamin belonging to the vitamin B family.

Cyproheptadine is a potent and orally active antagonist of 5-HT2A receptor with antiserotonergic and antidepressant effects. It also exhibits antiplatelet activities and has the potential to treat thromboembolic and depressive disorders.

Cenacitinib is an orally potent and selective allosteric inhibitor of tyrosine kinase 2 (Tyk2). It exhibits significant efficacy and can be used in research for the treatment of moderate to severe psoriasis.

Cefamandole (sodium) is a parenteral, broad-spectrum, second-generation cephalosporin antibiotic effective against various gram-positive and gram-negative bacteria, including Neisseria, Haemophilus, and Proteus species.

BKT-300 is a potent and selective inhibitor of Protein regulator of cytokinesis 1 (PRC1) with a Kd of 28.3 nM. It disrupts microtubule organization, inducing G2/M arrest, mitotic catastrophe, and caspase-3–dependent apoptosis, and shows promise as a research treatment for advanced acute myeloid leukemia (AML).

ATP dimagnesium (Adenosine 5'-triphosphate dimagnesium) is a central molecule in energy metabolism, driving cellular pumps and acting as a coenzyme. It also functions as an endogenous signaling molecule that modulates immune responses and activates the NLRP3 inflammasome, contributing to host defense during bacterial infections.

ABD0171 is a potent, irreversible, and selective inhibitor of aldehyde dehydrogenase 1A3 (ALDH1A3), with an IC50 of 0.34 µM using the physiological substrate all-trans-retinaldehyde (atRAL). It also inhibits ALDH1A2 and ALDH1A1 with IC50 of 0.79 µM and 6.6 µM, respectively. ABD0171 disrupts key oncogenic pathways in triple-negative breast cancer (TNBC) cells in vitro and exhibits robust antitumor and antimetastatic activity in vivo.

6K465 is a pyrimidine-based inhibitor of Aurora A, that reduces levels of c-MYC and N-MYC oncoproteins. It demonstrates compelling antitumor efficacy.

2-bromoethanol-d4 is the deuterated derivative of 2-bromoethanol. 2-bromoethanol is a cytotoxic alkylating agent.

1-Methyl-1,4-piperazine-d8 is the deuterated derivative of 1-methyl-piperazine.

(S)-Terazosin is a potent and selective antagonist of α-adrenoceptor with Ki values of 3.91 nM, 0.79 nM and 1.16 nM for α1a, α1b and α1d-adrenoceptor, respectively. It also has high-affinity for α2a, α2B and α2c-adrenoceptor with Ki values of 729 nM, 3.5 nM and 46.4 nM, respectively. It may prove to be a useful probe in understanding the functional role of subtypes of adrenoceptors in various tissues.

(D5)epichlorohydrin is the deuterated form of epichlorohydrin. Epichlorohydrin is a highly toxic industrial raw material with alkylating activity.

Trimecaine, a local neural blockade agent, has a strong depressant effect on the cerebral cortex and the ascending reticular formation of the brain stem.

Triglyceride OLO,sn (Compound 2) is a triglycerides that can be isolated from Dirca palustris.

SU-740 is a chalcone derivative with anti-ulcer activity.

Sporidesmolide III is a cyclodepsipeptide originally isolated from P. chartarum.

PSSI-51 is an orally active, peripherally selective inhibitor of succinyl-CoA:3-ketoacid-CoA transferase (SCOT). PSSI-51 inhibits SCOT activity in peripheral tissues (such as muscle and kidney) but does not affect SCOT activity in brain tissue. PSSI-51 reduces ketone body oxidation by inhibiting SCOT, thereby improving obesity-related hyperglycemia. PSSI-51 can be used in the study of type 2 diabetes (T2D) and has the potential to improve obesity-related metabolic disorders.

Phenylacetyl Coenzyme A (Phenylacetyl Coenzyme A) tetrasodium is an effector molecule of the TetR family transcriptional repressor PaaR. Phenylacetyl Coenzyme A tetrasodium changes the conformation of PaaR, causing it to dissociate from DNA and initiate transcription. Phenylacetyl Coenzyme A tetrasodium is promising for research of microbial metabolism.