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Cat. No. Product Name Field of Application Chemical Structure
DC32431 PD173952
PD173952 is a Src family kinase inhibitor.
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DC32430 NP603
NP603 is a cell-permeable inhibitor of PDGFRβ, FGFR1 and VEGFR2 that binds to ATP pocket. NP603 is a very weak inhibitor of EGFR
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DC32429 GW2974
GW2974 Potent and selective dual inhibitor of EGFR.
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DC32428 DMH4
DMH4 is a potent VEGF inhibitor and an angiogenesis inhbitor.
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DC32426 Calcon
Calcon is a biochemical indicator of calcium.
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DC32425 Alizarine Yellow R
Alizarine Yellow R is a yellow colored azo dye made by the diazo coupling reaction.
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DC32424 Oxazole yellow
Oxazole yellow is a fluorescent cyanine dye that binds to DNA and is used to detect apoptotic cells. Oxazole yellow does not enter live cells. However, during apoptosis the cytoplasmic membrane becomes slightly permeable, allowing entry of the dye. Oxazole yellow is often used along with propidium iodide (catalog no. P4170), a DNA dead cell stain that does not enter either live or apoptotic cells. The λEx/λEm of Oxazole yellow is 491/509.
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DC32423 Midecamycin
Midecamycin is a naturally occurring 16-membered macrolide that fits under the category of acetoxy-substituted macrolide antibiotics. In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position 4 of the terminal sugar.
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DC32422 Josamycin
Josamycin is a macrolide antibiotic.
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DC32421 L 709049
L 709049 is a biochemical.
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DC32420 Yau 17
Yau 17 is a biochemical.
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DC32419 Yatein
Yatein is a natural product isolated from from Cleistanthus boivinianu or Chamaecyparis obtusa. Yatein suppresses herpes simplex virus type 1 replication in HeLa cells by interruption the immediate-early gene expression. The mechanisms of antiviral action of yatein seem to be mediated, by inhibiting HSV-1 α gene expression, including expression of the ICP0 and ICP4 genes, and by arresting HSV-1 DNA synthesis and structural protein expression in HeLa cells. Yatein showed antiproliferative activity against the HCT-116 human colon carcinoma cell line, with an IC50 > 10 uM.
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DC32418 Molinate
Molinate is a biochemical.
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DC32417 Carbofuran
Carbofuran is one of the most toxic carbamate pesticides.
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DC32416 Yakkasterone
Yakkasterone is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone.
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DC32415 Niraxostat
Niraxostat is a biochemical.
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DC32414 Y 27152
Y 27152 is a biochemical.
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DC32412 Propham
Propham is a biochemical.
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DC32411 N-Benzyloxycarbonylglycine
N-Benzyloxycarbonylglycine
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DC32410 Polaprezinc
Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS).
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DC32409 Ziram
Ziram, also known as Zinc dimethyldithiocarbamate, is a coordination complex of zinc with dimethyldithiocarbamate. It is a pale yellow solid that is used as a fungicide, the vulcanization of rubber, and other industrial applications.
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DC32406 Caerulein
Caerulein is a specific decapeptide obtained from the skin of Hila caerulea, an Australian amphibian. Caerulein is similar in action and composition to CHOLECYSTOKININ. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. It is used in paralytic ileus and as diagnostic aid in pancreatic malfunction.
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DC32401 Nafamostat free base
Nafamostat, also known as FUT-175, is a serine protease inhibitor and an anticoagulant. Nafamostat promotes endothelium-dependent vasorelaxation via the Akt-eNOS dependent pathway. Nafamostat Attenuates Ischemia-Reperfusion-Induced Renal Injury. Nafamostat Attenuates Ischemia-Reperfusion-Induced Renal Injury. Nafamostat protects against acute cerebral ischemia via blood-brain barrier protection. Nafamostat Inhibits TNF-α-Induced Vascular Endothelial Cell Dysfunction by Inhibiting Reactive Oxygen Species Production. Researchers have identified the drug as a potential therapy for COVID-19,[ with clinical trials in Japan possibly set to begin in March 2020.
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DC32400 Segetalin B
Segetalin B is natural product isolated from Seeds of Vaccaria Segetalis. Segetalin B demonstrated to have an estrogen-like activity.
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DC32399 Danshenxinkun A
Danshenxinkun A is a natural diterpenoid isolated from the roots of Salvia miltiorrhiza Bge.
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DC32398 BCX 2600
Stiripentol (marketed as Diacomit by Laboratoires Biocodex) is an anticonvulsant drug used in the treatment of epilepsy. It is approved for the treatment of Dravet syndrome, an epilepsy syndrome. Stiripentol increases GABAergic activity. At clinically relevant concentrations, it enhances central GABA neurotransmission through a barbiturate-like effect, since it increases the duration of opening of GABA-A receptor channels in hippocampal slices.
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DC32396 LBH589 lactate
Panobinostat, also known as NVP LBH-589 or LBH-589, is a cinnamic hydroxamic acid analogue with potential antineoplastic activity. Panobinostat selectively inhibits histone deacetylase (HDAC), inducing hyperacetylation of core histone proteins, which may result in modulation of cell cycle protein expression, cell cycle arrest in the G2/M phase and apoptosis. In addition, this agent appears to modulate the expression of angiogenesis-related genes, such as hypoxia-inducible factor-1alpha (HIF-1a) and vascular endothelial growth factor (VEGF), thus impairing endothelial cell chemotaxis and invasion.
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DC32394 Meropenem trihydrate
Meropenem is an ultra-broad spectrum injectable antibiotic used to treat a wide variety of infections, including meningitis and pneumonia. It is a beta-lactam and belongs to the subgroup of carbapenem, similar to imipenem and ertapenem. Meropenem was originally developed by Sumitomo Pharmaceuticals. It is marketed outside Japan by AstraZeneca with the brand names Merrem and Meronem. Other brand names include Zwipen (India, Marketed by Nucleus) Mepem (Taiwan) Meropen (Japan, Korea) and Neopenem (NEOMED India) . It gained FDA approval in July 1996. It penetrates well into many tissues and body fluids including the cerebrospinal fluid, bile, heart valves, lung, and peritoneal fluid.
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DC32390 Iristectorigenin A
Iristectorigenin A is an natural isoflavones, showing antioxidant activity.
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DC32389 Terphenyllin
Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has signi?cant α-glucosidase inhibitory activity.
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