To enhance service speed and avoid tariff delays, we've opened a US warehouse. All US orders ship directly from our US facility.
| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC32388 | (R)-Carisbamate |
(R)-Carisbamate is the R-isomer of Carisbamate . Carisbamate (YKP 509, proposed trade name Comfyde) is an experimental anticonvulsant drug that was under development by Johnson & Johnson Pharmaceutical Research and Development but never marketed.
More description
|
|
| DC32386 | Methylthialazole Tetrazolium |
Methylthialazole Tetrazolium, also known as MTT or Tetrazolium Bromide, is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells.1 It is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD(P)H-oxidoreductases. It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.
More description
|
|
| DC32385 | Picrocrocin |
Picrocrocin is a monoterpene glycoside precursor of safranal. Picrocrocin is found in the spice saffron, which comes from the crocus flower. Picrocrocin is a degradation product of the carotenoid zeaxanthin. Picrocrocin exhibits growth inhibitory effects against SKMEL- 2 human malignant melanoma cells by targeting JAK/ STAT5 signaling pathway, cell cycle arrest and mitochondrial mediated apoptosis.
More description
|
|
| DC32383 | α-Arbutin |
Arbutin is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos among many other medicinal plants, primarily in the family Ericaceae. Applied topically, it inhibits tyrosinase and thus prevents the formation of melanin. Arbutin is therefore used as a skin-lightening agent. Very tiny amounts of arbutin are found in wheat, pear skins, and some other foods. It is also found in Bergenia crassifolia. Arbutin was also produced by an in vitro culture of Schisandra chinensis. α-Arbutin Protects Against Parkinson's Disease-Associated Mitochondrial Dysfunction In Vitro and In Vivo.
More description
|
|
| DC32381 | Hesperidin Methyl Chalcone |
Hesperidin Methyl Chalcone is a derivative of the flavonoid hesperidin and is found in citrus fruits like oranges and grapefruit and is often used to reduce dark circles under the eyes.
More description
|
|
| DC32376 | Dihydrolipoic acid |
Dihydrolipoic acid, also know as DHLA, is a dithiol-containing carboxylic acid that is the reduced form of α-lipoic acid . It acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including hydroxyl radicals, peroxynitirite, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.
More description
|
|
| DC32375 | WR-238605 d3 |
Tafenoquine-d3 is a trideuerium-labeled Tafenoquine derivative. Tafenoquine, also known as WR-238605, is an oral active antimalaria drug that is being investigated as a potential treatment for malaria, as well as for malaria prevention. Tafenoquine Shows Activity against Trypanosoma brucei. Tafenoquine targets leishmania respiratory complex III and induces apoptosis. Tafenoquine has a long half-life of approximately 14 days and is generally safe and well tolerated, Malaria remains an important cause of global morbidity and mortality. As antimalarial drug resistance escalates, new safe and effective medications are necessary to prevent and treat malarial infection.
More description
|
|
| DC32372 | Hibifolin |
Hibifolin is a flavonol glycoside that prevents beta-amyloid-induced neurotoxicity in vitro. Hibifolin prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons. Hibifolin is a potential inhibitor of adenosine deaminase.
More description
|
|
| DC32371 | 69-23-8 (free base) |
Fluphenazine is a antipsychotic medication. It is used in the treatment of chronic psychoses such as schizophrenia. Fluphenazine exerts its actions by blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. This prevents the actions of dopamine, thereby reducing the hallucinations and delusions that are associated with schizophrenia. It is given by mouth, injection into a muscle, or just under the skin.
More description
|
|
| DC32369 | Triclopyr |
Triclopyr, also known as 3,5,6-Trichloro-2-pyridinyloxyacetic acid, is a systemic foliar herbicide and fungicide. Triclopyr is used to control broadleaf weeds while leaving grasses and conifers unaffected or to control rust diseases on crops.
More description
|
|
| DC32367 | Salvinorin A |
Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A preserves cerebral pial artery autoregulation after forebrain ischemia via the PI3K/AKT/cGMP pathway. Salvinorin A ameliorates cerebral vasospasm through activation of endothelial nitric oxide synthase in a rat model of subarachnoid hemorrhage.
More description
|
|
| DC32366 | Betamethasone acetate |
Betamethasone acetate, also known as Betamethasone 21-acetate, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is the 21-acetate ester of betamethasone.
More description
|
|
| DC32365 | Pseudopelletierine |
Pseudopelletierine is the main alkaloid derived from the root-bark of the pomegranate tree (Punica granatum), along with at least three other alkaloids: pelletierine, isopelletierine, and methylpelleteirine (C9H17ON), which yield 1.8, 0.52, 0.01, and 0.20 grams per kilogram of raw bark.
More description
|
|
| DC32364 | LY-237216 |
Dirithromycin is a macrolide glycopeptide antibiotic. Dirithromycin is a more lipid-soluble prodrug derivative of 9S-erythromycyclamine prepared by condensation of the latter with 2-(2-methoxyethoxy)acetaldehyde. The 9N, 11O-oxazine ring thus formed is a hemi-aminal that is unstable under both acidic and alkaline aqueous conditions and undergoes spontaneous hydrolysis to form erythromycyclamine.
More description
|
|
| DC32362 | 17-phenyl trinor Prostaglandin F2α |
Bimatoprost acid is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α.
More description
|
|
| DC32359 | Clobetasone Butyrate |
Clobetasone is a corticosteroid used in dermatology, for treating such skin inflammation as seen in eczema, psoriasis and other forms of dermatitis, and ophthalmology. Topical clobetasone butyrate has shown minimal suppression of the Hypothalamic-pituitary-adrenal axis. It is available as clobetasone butyrate under the brand names Eumosone or Eumovate both manufactured by GlaxoSmithKline.
More description
|
|
| DC32358 | Estradiol cypionate |
Estradiol cypionate, also known as Depoestradiol, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for transgender women, and in hormonal birth control for women. Estradiol cypionate was first described as well as introduced for medical use in 1952. Along with estradiol valerate, it is one of the most commonly used esters of estradiol.
More description
|
|
| DC32357 | Light Green SF Yellowish |
Light green SF yellowish (C.I. 42095) is a dye that is used for the preparation of a staining solution which is is widely used as a counterstain. for e.g. trichrome Masson-Goldner staining in histological sections or for Papanicolaou’s polychromatic staining in cytology of samples human origin
More description
|
|
| DC32356 | Lycoramine free base |
Lycoramine is a natural alkaloid isolated from Lycoris chinensis.
More description
|
|
| DC32355 | Di-Paralene |
Chlorcyclizine is a first-generation antihistamine of the phenylpiperazine class marketed in the United States and certain other countries. It is used primarily to treat allergy symptoms such as rhinitis, urticaria, and pruritus, and may also be used as an antiemetic. In addition to its antihistamine effects, chlorcyclizine also has some anticholinergic, antiserotonergic, and local anesthetic properties. It also has been studied as a potential treatment for hepatitis C.
More description
|
|
| DC32350 | Sodium aurothiomalate |
Sodium aurothiomalate (INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Along with an orally-administered gold salt, auranofin, it is one of only two gold compounds currently employed in modern medicine
More description
|
|
| DC32346 | MK 5172 potassium |
Grazoprevir, also known as MK5172, is a drug approved for the treatment of hepatitis C. Grazoprevir is a second generation hepatitis C virus protease inhibitor acting at the NS3/4a protease targets. It has good activity against a range of HCV genotype variants, including some that are resistant to most currently used antiviral medications.
More description
|
|
| DC32345 | Remogliflozin A |
Remogliflozin, also known as Remogliflozin A and GSK189074, is a potent inhibitor of sodium-glucose transporter 2 (SGLT2; Kis = 12.4 and 26 nM for human and rat SGLT2, respectively).
More description
|
|
| DC32344 | Alpha-Chloralose |
Alpha-Chloralose is an avicide, and a rodenticide used to kill mice in temperatures below 15 °C. It is also widely used in neuroscience and veterinary medicine as an anesthetic and sedative.
More description
|
|
| DC32343 | Norbormide |
Norbormide, also known as Raticate, Shoxin, is a toxic compound used as a rodenticide. It has several mechanisms of action, acting as a vasoconstrictor and calcium channel blocker, but is selectively toxic to rats and has relatively low toxicity to other species, due to a species specific action of opening the permeability transition pores in rat mitochondria.
More description
|
|
| DC32342 | GR-203040 |
GR-203040 is a selective NK1 receptor antagonist. GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder. GR203040 is a novel anti-emetic agent, and the broad spectrum of anti-emetic activity, together with activity observed in three species, suggests that this compound is worthy of clinical investigation.
More description
|
|
| DC32339 | Desmethyltramadol HCl |
Desmetramadol is a central analgesic drug candidate. Desmetramadol inhibits 5-hydroxytryptamine type 2C receptors expressed in Xenopus Oocytes.
More description
|
|
| DC32338 | Gabaculine HCl |
Gabaculine is a naturally occurring, conformationally constrained analog of GABA and an irreversible inhibitor of GABA transaminase (GABA-T; Ki = 2.9 μM). Gabaculine alters plastid development and differentially affects abundance of plastid-encoded DPOR and nuclear-encoded GluTR and FLU-like proteins in spruce cotyledons.
More description
|
|
| DC32337 | Chlorotoluron |
Chlorotoluron is a pheylurea herbicide that has been used to control growth of broad-leaved weeds in winter wheat, rye, barley, and triticale crops.
More description
|
|
| DC32335 | Morin Hydrate |
Morin is a yellow chemical compound that can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava). In a preclinical in vitro study, morin was found to be a weak inhibitor of fatty acid synthase with an IC50 of 2.33 μM. Morin was also found to inhibit amyloid formation by islet amyloid polypeptide (or amylin) and disaggregate amyloid fibers. Morin can be used to test for the presence of aluminium or tin in a solution, since it forms characteristically fluorescent coordination complexes with them.
More description
|
|