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Cat. No. Product Name Field of Application Chemical Structure
DC34469 Enbucrilate
Enbucrilate is a tissue adhesive, forming polymer films at oil-water interfaces and revealing films of diverse morphology.
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DC37642 Diiodotyrosine
Diiodotyrosine (DIT) is a precursor in the production of thyroid hormone, and results from iodization of monoiodotyrosine at the other meta- position on the phenol ring.
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DC35474 THP-PEG9
THP-PEG9 is a PEG Linker.
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DC35963 PEG5-Ms
PEG5-Ms is a PEG Linker.
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DC37905 Glycyltyrosine
Glycyltyrosine is a dipeptide composed of glycine and tyrosine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.
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DC35136 Bis-PEG1-NHS ester
Bis-PEG1-NHS ester is a PEG derivative containing two NHS ester groups. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35137 Bis-PEG2-NHS ester
Bis-PEG2-NHS ester is a PEG derivative containing two NHS ester groups. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. PEG Linkers may be useful in the development of antibody drug conjugates (ADCs).
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DC37508 Racemetirosine
Racemetirosine is an inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines.
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DC37008 Fluopyram
Fluopyram is a fungicide.
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DC36933 Acridine Orange NS
Acridine Orange is a cationic cytochemical stain specific for cell nuclei, especially DNA. It is used as a supravital stain and in fluorescence cytochemistry. It may cause mutations in microorganisms.
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DC34662 Chromonar hydrochloride
Chromonar hydrochloride is a coronary vasodilator agent. It increases in transmural blood flow.
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DC36742 Salicylamide
Salicylamide is a non-steroidal anti-inflammatory agent with analgesic and antipyretic properties. Its medicinal uses are similar to those of aspirin.
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DC34201 MS21570
MS21570 is a GPR171 antagonist that reduces anxiety-like behavior and fear conditioning in mice.
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DC36788 Norgestrel
Norgestrel is a synthetic progestational agent with actions similar to those of PROGESTERONE. This racemic or (±)-form has about half the potency of the levo form (LEVONORGESTREL). Norgestrel is used as a contraceptive, ovulation inhibitor, and for the control of menstrual disorders and endometriosis.
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DC37068 Butaperazine
Butaperazine (Repoise, Tyrylen) is a typical antipsychotic of the phenothiazine class.
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DC36315 N-Dipropyldopamine hydrobromide
N,N-Dipropyldopamine HBr is a dopamine receptor agonist. It decreases dihydrophenylalanine (DOPA) levels in the limbic forebrain and striatum as well as reduces homovanillic acid (HVA) levels. N,N-Dipropyldopamine reduces spontaneous locomotor activity in mice, an effect that can be reversed by the antipsychotic spiroperidol.
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DC34158 Isosorbide
Isosorbide is a precursor of Isosorbide mononitrate or dinitrate, which relax vascular smooth muscle by formation of the free radical nitric oxide (NO).
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DC33724 NQN-1
NQN-1 is a histone deacetylases-6 (HDAC6) inhibitor and nuclear factor-κB (NF-κB) activation blocker.
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DC37990 Kemptide
Kemptide is a heptapeptide used as substrate for cAMP dependent protein kinase.
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DC35582 m-PEG8-thiol
m-PEG8-thiol is a PEG derivative containing a thiol group. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC36825 Jedi2
Jedi2 is a Piezo1 channel activator that promotes Ca2+ influx into HEK293 cells expressing Piezo1 channels and elicits responses in mouse Piezo1-transfected, but not Piezo2-transfected cells.
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DC38080 SMCC
SMCC, also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a heterobifunctional protein crosslinker. SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane-stabilized spacer arm (8.3 angstroms). SMCC conjugation occurs via a maleimide group that is sulfhydryl (thiol; -SH) reactive and a NHS ester group that is amine reactive and forms stable, covalent protein crosslinks.
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DC35843 4-((2,5-Dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid
4-((2,5-Dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC34220 Moxalactam Disodium
Moxalactam Disodium is a broad- spectrum beta-lactam antibiotic.
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DC34074 LSF
Lisofylline, also known as LSF, improves cellular mitochondrial function and blocks interleukin-12 (IL-12) signaling and STAT-4 activation in target cells and tissues. IL-12 and STAT-4 activation are important pathways linked to inflammation and autoimmune damage to insulin producing cells. Therefore, LSF and related analogs could provide a new therapeutic approach to prevent or reverse type 1 diabetes.
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DC31804 Pentoxifylline
Pentoxifylline is a drug used to treat muscle pain in people with peripheral artery disease. Like other methylated xanthine derivatives, pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity. It is being investigated for treatment of Alzheimer's disease. It is generic and sold under many brand names worldwide.
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DC34491 Halofuginone HBr
Halofuginone Hydrobromide is a potent prolyl-tRNA synthetase inhibitor.
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DC37832 Methyl leucylleucinate hydrochloride
Methyl leucylleucinate HCl is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells.1,2 It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid tumor cells.2 Upon entry into cells via receptor-mediated endocytosis, LLME undergoes a condensation process catalyzed by dipeptidyl peptidase I (DPPI) in lysosomes. This condensation leads to lysosomal rupture and DNA fragmentation in DPPI-expressing immune cells such as cytotoxic T cells and natural killer cells.2
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DC36314 Urapidil HCl
Urapidil HCl is an antagonist of α1-adrenergic receptors (α1-ARs) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. Urapidil HCl inhibits cAMP accumulation induced by forskolin. It is also a β1-AR antagonist that inhibits the positive chronotropic response induced by isoproterenol. Urapidil HCl lowers mean arterial pressure (MAP) in anesthetized cats, an effect that is reduced by central administration of the 5-HT1A receptor antagonist spiroxatrine.
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DC37725 (-)-Carvone
(-)-Carvone is one of the key constituents of spearmint (Mentha spicata) oil. Studies indicate that it is a potent feeding-deterrent to stored product beetles
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