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Cat. No. Product Name Field of Application Chemical Structure
DC40458 GSHtracer
GSHtracer is a ratiometric probe for measuring of GSH levels. GSHtracer exhibits Ex/Em from 520/580 nm to 430/510 nm (upon GSH binding) .
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DC40457 Fluorescein-NAD+
Fluorescein-NAD+ is an alternative to radiolabeled NAD and a substrate for ADP-ribosylation. Fluorescein-NAD+ can be used in PARP assays by fluorescence microscopy. Extinction Coefficient: 262 nm.
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DC40456 Fluorescein tyramide
Fluorescein tyramide is a green fluorescent reagent (λabs: 494 nm; λem: 517 nm). Fluorescein tyramide is widely used for tyramide signal amplification (TSA) with a low-abundance in IHC, ICC, in situ hybridization (FISH) and flow cytometry (FCM) applications.
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DC40455 Puwainaphycin F
Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization.
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DC40454 Microcolin B
Microcolin B is an extremely potent unusual acylpeptide, proline-containing potent immunosuppressant. Microcolin B is isolated from blue-green alga Lyngbya majuscule.
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DC40453 Tolytoxin
Tolytoxin, a bioactive metabolite from cyanobacteria, is a potent antifungal antibiotic, exhibiting MICs of 0.25-8 nmol. Tolytoxin is a cyanobacterial macrolide that targets actin by inhibition of its polymerization. Tolytoxin has cytotoxic effects in cancer cells.
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DC40452 17-GMB-APA-GA
17-GMB-APA-GA is an ADC Cytotoxin. 17-GMB-APA-GA is a potent HSP90 inhibitor and used for latent T. gondii infection research.
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DC40451 Diacetyl Agrochelin
Diacetyl Agrochelin is an acetyl derivative of Agrochelin, which is produced by the fermentation of a marine Agrobacterium sp. Diacetyl Agrochelin has cytotoxic activity in tumor cell lines.
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DC40450 Aeruginosin 865
Aeruginosin 865, isolated from terrestrial cyanobacterium Nostoc sp. Luke?ová 30/93, is the first aeruginosin-type peptide containing both a fatty acid and a carbohydrate moiety. Aeruginosin 865 inhibits translocation of NF-kB to the nucleus. Aeruginosin 865 has anti-inflammatory effect
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DC40449 Isatropolone A
Isatropolone A, a natural product containing a 1,5-diketone moiety, is reisolated from Streptomyces G?66. Isatropolone A shows potent activity against Leishmania donovani with an IC50 of 0.5 μM.
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DC40448 Androgen receptor antagonist 1
Androgen receptor antagonist 1 is an orally available full androgen receptor (AR) antagonist with an IC50 of 59 nM. Androgen receptor antagonist 1 (Compound 6) can be used in the synthesis of PROTAC AR degraders, which results 24% and 47 % AR protein degradation in LNCaP cells at 1 μM and 10 μM, respectively.
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DC40446 Duocarmycin DM
Duocarmycin DM, a DNA minor-groove alkylator, is an antibody drug conjugates (ADCs) toxin. Duocarmycin DM is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.
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DC40445 Tetrazine-PEG4-amine hydrochloride
Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40444 Boc-Val-Dil-Dap-Phe-OMe
Boc-Val-Dil-Dap-Phe-Ome is an ADC Cytotoxin.
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DC40443 Ald-Ph-PEG4-bis-PEG3-methyltetrazine
Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40442 Mal-PEG4-bis-PEG4-propargyl
Mal-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40441 Amino-bis-PEG3-DBCO
Amino-bis-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40440 Mal-PEG4-bis-PEG3-DBCO
Mal-PEG4-bis-PEG3-DBCO is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40439 Amino-PEG4-bis-PEG3-methyltetrazine
Amino-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40438 Ald-Ph-PEG4-bis-PEG3-N3
Ald-Ph-PEG4-bis-PEG3-N3 is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40436 Ald-Ph-PEG4-bis-PEG4-propargyl
Ald-Ph-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40435 Boc-Val-Dil-Dap-OH
Boc-Val-Dil-Dap-OH is an ADC Cytotoxin.
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DC40434 Boc-NMe-Val-Val-Dil-Dap-OH
Boc-NMe-Val-Val-Dil-Dap-OH is an ADC Cytotoxin.
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DC40433 Thalidomide-O-C8-COOH
Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs.
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DC40432 HS-PEG3-CH2CH2NH2 hydrochloride
HS-PEG3-CH2CH2NH2 hydrochloride (Thiol-PEG3-amine hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40430 Thalidomide-NH-PEG2-C2-NH-Boc
Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the?Thalidomide?based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology.
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DC40428 Pomalidomide 4'-alkylC5-acid
Pomalidomide 4'-alkylC5-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a PEG linker used in PROTAC technology.
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DC40427 Tachysterol 3
Tachysterol 3 is a side product in vitamin D photosynthesis.
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DC40426 Previtamin D3
Previtamin D3 is an intermediate in the production of cholecalciferol (vitamin D3).
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DC40425 Isotachysterol 3
Isotachysterol 3 is an analog of 1,25-dihydrox Vitamin D3. Isotachysterol 3 stimulates intestinal calcium transport and bone calcium mobilization in anephric rats.
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