NSC 23925 is a small molecule compound that reverses multiple drug resistance (MDR) in human cancer cell lines, reverses MDR1 (Pgp1) but does not inhibit MRP or BCRP-mediated MDR.

NSC 19630 (MIRA-1) is a potent, selective Werner syndrome helicase (WRN helicase) with IC50 of 20 uM.

NSC 191412 is a bioactive compound.

NSC 15765 (Compound C5, DNA2 inhibitor C5) is an effective, selective and competitive inhibitor of DNA2 nuclease with IC50 of 20 uM.

NSC 146268 (NSC146268, 6-Aza-2-thiouridine) is a novel small molecule inhibitor of CD151, inhibits proliferation of metastatic triple negative breast cancer cell lines (MDA-MB 231 and MDA-MB 468, IC50 of 6.0 and 6.2 ug/mL).

NSC 145366 is a novel, allosteric Hsp90 CTD (C-terminal domain) inhibitor, exhibits anti-proliferative activity in tumor cell lines with GI50 of 0.2-1.9 uM.

NS-3-008 hydrochloride is a novel small-molecule transcriptional inhibitor of G0s2 (G0/G1 switch 2) with IC50 of 2.25 uM.

NS-062 (NS062) is a novel, specific targeted covalent inhibitor that shows high reactivity toward Cys797 of EGFR.

NS-018 hydrochloride (NS018, Ilginatinib) is a potent and highly selective JAK2 inhibitor (IC50=0.72 nM).

NS-018 (NS018, Ilginatinib) is a potent and highly selective JAK2 inhibitor (IC50=0.72 nM).

NS 2028 is a specific inhibitor of soluble guanylyl cyclase.

Nrf2 activator 16 is a potent Keap1-Nrf2 and Keap1-p-p62 protein-protein interaction inhibitor with IC50 of 0.91 uM and 1.8 uM respectively.

Nrf2 acticatior AI-1 is a small-molecule inducer of the antioxidant response element (ARE) that activates and stabilizes Nrf2 by covalently modifying Keap1, activates an ARE-dependent luciferase reporter with an EC50 of 2.7 uM.

NPS 2143 hydrochloride is a selective CaSR (Ca2+-sensing receptor) inhibitor and antagonist, shown to block increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells with an IC50 of 43 nM. NPS 2143 hydrochlori

NPD13668 (NPD-13668) is a chemical novel modulator of EZH2-mediated gene silencing, inhibits EZH2/PCR2 activity and decreases H3K27me3 levels.

NOSO-502 (NOSO502) is a novel inhibitor of bacterial translation, has MIC values of 0.5-4 ug/ml against standard Enterobacteriaceae strains and carbapenem-resistant Enterobacteriaceae (CRE) isolates that produce KPC, AmpC, or OXA enzymes and metallo-β-lactamases.

Nosiheptide is a bicyclic thiopeptide antibiotic produced by several species of actinomycetes, notably Streptomyces.

Norethindrone is a synthetic progestin, which mimic the actions of the endogenous ovarian hormone progesterone.

Nootropic agent shown to exhibit learning and memory improvement and cognitive function impairment prevention. Mechanism of action has not been quantified, but current theories suggest a modulation of glutamatergic and cholinergic neurotransmissions with

Noopept (GVS-111) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic.

non-nucleoside inhibitor of the NS5B

N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte.

NNC-0640 (NNC 0640, NNC0640) is a potent, selective glucagon receptor (GCGR) negative allosteric modulator with IC50 of 69.2 nM.

NMT1 inhibitor B13 (LCL4) is a myristoylCoA analog that acts as a small molecule inhibitor of NMT1 with IC50 of 77.6 uM, blocks Src myristoylation and Src localization to the cytoplasmic membrane.

NMS-P645 is a novel selective inhibitor of pan-Pim kinases with IC50 of 3/73/12 nM for Pim1/2/3, respectively.

NMS-P293 is a novel potent and selective PARP-1 inhibitor possessing >200-fold selectivity versus PARP-2.

NMI 8739 is a dopamine D2 autoreceptor agonist, which is an amine conjugate of the DHA carrier and the neurotransmitter dopamine.

NMac1 (Nm23 activator 1) is a small molecule activator of Nm23/NDPK, directly binds to Nm23-H1 and activates NDPK activity of recombinant Nm23-H1 with EC50 of 10.7 uM.

NLY01 (NLY-01, GLP1R agonist NLY01) is a potent, brain-penetrant long-acting GLP1R agonist, protects against the loss of dopaminergic neurons and behavioral deficits in the α-synuclein preformed fibril (α-syn PFF) mouse model of sporadic Parkinson's disea

NLRP3 Inflammasome Inhibitor I, an intermediate substrate in the synthesis of glyburide which is free of the cyclohexylurea moiety involved in insulin release, is a novel inhibitor of the NLRP3 inflammasome.