FN075 is a small-molecule inhibitor targeting Escherichia coli amyloid biogenesis and biofilm formation.

Fluvoxamine maleate is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.

Fluvastatin, Sodium Salt is a synthetic inhibitor of HMGCR (HMG-CoA reductase) (IC50 = 40-100 nM for human liver microsomes) that acts as an anti-hypercholesterolemic compound and as an antioxidant. Fluvastatin also inhibits induction of the LDL receptor

Fluticasone propionate (Flonase, Veramyst)

Flurbiprofen (Ansaid)

Flupirtine maleateis a non-opioid, centrally acting analgesia, muscle relaxation and neuroprotection. Currently under a clinical trial (recruiting phase) as a treatment for Multiple Sclerosis and has been used as an analgesic.

Fluocinonide(Vanos)

Fluocinolone acetonide (Flucort-N)

Flumequine

Flumazenil(Ro 15-1788) is a benzodiazepine antagonist, non-selective for α1, α2, α3 or α5-containing GABAA receptors.

Flucytosine (5-Fluorocytosine, 5-FC, Ancobon) is an antifungal drug with IC50 of 0.12 μg/mL in C.albicans.

Fluconazole

Flubendazole is a potent broad spectrum anthelmintic.

FLT3-IN-5e is a nove potent, selective FLT3 inhibitor with Kd of 3.6 nM, IC50 of <6 nM.

Fleroxacin (Quinodis)

Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression.

Flagelin 22 TFA, a fragment of bacterial flagellin, is an effective elicitor in both plants and algae.

FKGK18 (FKGK18) is a potent, selective inhibitor of iPLA2 (group VIA Ca2+-independent phospholipase A2) with IC50 of 50 nM.

FJ 5002 is a potent telomerase inhibitor with IC50 of 2 uM, a close derivative of MKT077.

Firocoxib(ML 1785713) is a potent and selective cyclooxygenase (COX)-2 inhibitor with IC50 of 0.13 uM, 58 fold sensitivity for COX2 VSCOX1.

Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 and 1,600 nM for cockroach and rat receptors, respectively).

Fingolimod(FTY720 free base) is a S1P antagonist with IC50 of 0.033 nM.

Finazine is a high-affinity, brain penetrant sigma-1 and sigma 2 receptor ligand with Ki of 2.6 nM and 46 nM, respectively.

FimH inhibitor 5h is a potent and orally active FimH inhibitor.

Filibuvir (PF-00868554.

Filaminast (WAY-PDA-641.

Fidarestat (SNK860) is a potent aldose reductase inhibitor, improves motor nerve conduction velocity (MNCV) and metabolic abnormalities in sciatic nerve were investigated in acute STZ-induced diabetic rats..

Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells..

FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).

FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).