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DC20209 | Octodrine hydrochloride Featured |
Octodrine (2-Amino-6-methylheptane) is a central nervous activator that increases the uptake of dopamine and noradrenaline. Octodrine is found to increase the pain threshold, cardiac rate (positive chronotropic effect) and myocardial contractility (positive inotropic effect).
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DC67160 | 1-Bromodibenzofuran Featured |
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DC67159 | Thioxanthen-9-one Featured |
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DC50036 | RAD-150 Featured |
RAD150 is a nonsteroidal androgen receptor modulator (IC50 = 130 nM) and benzoate ester derivative of the selective androgen receptor modulator (SARM) RAD140.
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DC42084 | Phenazine methylsulfate Featured |
Phenazine methylsulfate is a free radical generator. Phenazine methylsulfate has been used as an electron transfer reactant in cell viability assays. Phenazine methylsulfate induces ssDNA break formation in the presence of the reducing agent NADPH. Phenazine methylsulfate induces oxidative DNA damage in an alkaline comet assay and apoptosis.
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DC9738 | GSK2881078 Featured |
GSK-2881078 is an orally active and nonsteroidal selective androgen receptor modulator (SARM) which act as partial AR agonists in androgenic tissues while mainly as complete AR agonists in synthetic metabolic tissues,induces AR-mediated transcriptional activation in PC3(AR)2 cells (EC50 = 3.99 nM) and the effect can be inhibited by the non-steroidal AR antagonist Bicalutamide. GSK-2881078 can be used in research of muscle weakness and cachexia associated with both chronic and acute illness.
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DC9904 | GW0742 Featured |
GW0742 is a potent PPARβ and PPARδ agonist, with an IC50 of 1 nM for human PPARδ in binding assay, and EC50s of 1 nM, 1.1 μM and 2 μM for human PPARδ, PPARα, and PPARγ, respectively.
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DC67158 | ANTHRACENE, 9-[1,1'-BIPHENYL]-2-YL- Featured |
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DC67157 | Dibenzo[b,d]furan-1-ylboronicacid Featured |
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DC67156 | tert-Butyl 3-formylpyrrolidine-1-carboxylate Featured |
tert-Butyl 3-formylpyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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DC32798 | PF-06260414 Featured |
PF-06260414 is a selective androgen receptor modulator, or SARM, which is developed to treat muscle weakening. Testosterone’s anabolic properties help develop muscle mass, and its androgenic activity is associated with reproduction. Improving muscle mass would improve quality of life and may even prolong survival in certain patient populations.
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DC67155 | 3-(dibenzo[b,d]furan-4-yl)phenyl)boronic acid Featured |
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DC23720 | LY2452473 Featured |
LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM).
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DC67154 | OTE-AC Featured |
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DC67153 | 5-nitrothiophene-2-carbaldehyde Featured |
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DC67152 | Octopamine Featured |
Octopamine is an alpha-adrenergic sympathomimetic amine biosynthesized from tyramine. Octopamine may be found in the CNS, platelets, and in invertebrate nervous systems. It is used to treat hypotension and may acy as a cardiotonic.
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DCAPI1311 | Indole-3-carbinol Featured |
Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).
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DC23578 | S-18986 Featured |
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests.
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DC67151 | 2-Chloro-4-fluoro-3-methylbenzonitrile Featured |
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DC67150 | (2R)-3-Bromo-2-hydroxy-2-methylpropanoic acid Featured |
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DC37590 | N,N-Diethylphenethylamine Featured |
N,N-Dimethylphenethylamine (N,N-DMPEA) is a substituted phenethylamine that is used as a flavoring agent.
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DC67149 | DL-N-Isopropyloctopamine Featured |
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DCY-016 | Yohimbine hydrochloride Featured |
Yohimbine hydrochloride is an alpha-2 renal adenomatase receptor inhibitor, blocking pre- and post-contact alpha-2 renal adenomatase receptors, causing the release of renal adenoma and multiple sclerosis.
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DC67148 | 4-Nitro-3-(trifluoromethyl)aniline Featured |
4-Nitro-3-(trifluoromethyl)aniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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DC10810 | Pyrroloquinoline quinone (PQQ) Featured |
Pyrroloquinoline quinone (PQQ) is used as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s).
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DC65829 | Tetramethyluric acid Featured |
Tetramethyluric acid (1,3,7,9-Tetramethyluric acid; Theacrine), also known as tetramethyluric acid or theophylline, is a purine alkaloid with a structure similar to caffeine. Tetramethyluric acid is a biomaterial or organic compound that can be used as a research-related biomaterial or organic compound in life sciences.
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DCT-004 | Crustecdysone Featured |
Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP. Crustecdysone exhibits regulatory or protective roles in the cardiovascular system. Crustecdysone is an active metabolite of Ecdysone (HY-N0179).
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DC32306 | Synephrine HCl Featured |
Synephrine, or, more specifically, p-synephrine, is an alkaloid, occurring naturally in some plants and animals, and also in approved drugs products as its m-substituted analog known as neo-synephrine. p-Synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine. This substance is present at very low concentrations in common foodstuffs such as orange juice and other orange (Citrus species) products, both of the "sweet" and "bitter" variety.
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DC32163 | Ipriflavone Featured |
Ipriflavone, also known as Yambolap and FL-113, is an osteoclast inhibitor and is effective for enhancing osteoblastic bone formation.
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DC8122 | Andarine (GTX-007,S-4) Featured |
GTx-007 (S-4) is an orally active and selective nonsteroidal androgen receptor (AR) modulator (SARM) and a partial agonist, with Ki of 4 nM. GTx-007 (S-4) is identified as SARMs with potent and tissue-selective in vivo pharmacological activity.
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