Novel inhibitor of SARS-CoV-2 main protease (MPro)

Novel glucose transport inhibitor

Novel Lysine-Specific Demethylase 1 (LSD1) Inhibitor (IC50: 20nM)

Novel inhibitor of vanilloid receptor subtype 1 (VR1)

Novel inhibitor of SARS-CoV-2 main protease (MPro)

Novel potent and selective glucagon receptor antagonist

Novel histamine H3-receptor antagonist

Inhibitor of p21-hRas nucleotide exchange in vitro

Novel Acyl_carrier_protein_synthase>acyl carrier protein synthase inhibitor; Inhibitor of growth of the bacteria Streptococcus_pneumoniae>Streptococcus pneumoniae and Neisseria_gonorrhoeae>Neisseria gonorrhoeae

Potent and selective PDE1 and PDE5 inhibitor

Non-​nucleoside antiviral agent, having potent and selective activity against herpes simplex virus type 2 (HSV-​2)

Novel, orally active phosphodiesterase 4 (PDE4) inhibitor

D1 dopamine receptor antagonist

Precursor for radioiosotopically labelled R(+)-SCH-23390

Novel Inhibitor of the virus fusion to its cell receptor, targeting SARS-CoV-2 spike protein HR1

Novel Inhibitor of the virus fusion to its cell receptor, targeting SARS-CoV-2 spike protein HR1

Natural selective non-peptide antagonist for the receptor GAL-1

Natural Potent Inhibitor of Transient Receptor Potential Melastatin 2 (TRPM2) Ion Channels

Novel photoswitchable substrate for sphingomyelin synthase 2 (SMS2), enabling optical control of apoptosis and being ready for azide-alkyne click chemistry

Novel photoswitchable substrate for sphingomyelin synthase 2 (SMS2), enabling optical control of apoptosis and being ready for azide-alkyne click chemistry

Novel selective COX-2 inhibitor

Potent and selective inhibitor of p38 MAP kinase

Selective COX-2 inhibitor

Second-generation leukotriene B4 receptor antagonist

Matrix metalloproteinase (MMP) inhibitor, also acting as a collagenase inhibitor

Potent inhibitor of checkpoint kinase 2 (Chk2)

Novel obatoclax derivative, inducing apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation

Novel Smac mimetic, demonstrating potent cell-killing effects in several subtypes of breast, ovarian, and prostate cancer cell lines but only when the DR ligand TRAIL or another such apoptosis inducer is co-administered

Inhibitor of S100B which selectively kills melanoma; Amoebicidal diamidine

Novel inhibitor of Quiescin Sulfhydryl Oxidase 1 (QSOX1), suppresses tumor cell growth in a Matrigel-based spheroid assay and inhibits invasion in a modified Boyden chamber, but does not affect viability of non-malignant cells