Selective 5-HT4 receptor antagonist

Novel PI3K inhibitor, synergizing with sorafenib in non-small cell lung cancer cells involving the Akt-S6 signaling.

Novel potent PI3K inhibitor with a modified omipalisib structure

Highly potent ATP-competitive PI3Kdelta/Vps34 dual inhibitor

Novel Inhibitor of the PI3K-Akt Pathway, Inducing Autophagy of Female Germline Stem Cells

Novel inhibitor of the PI3K/Akt/mTOR signaling pathways, activating P53 and inducing apoptosis

Novel Tau ligand, displaying high Tau binding, low MAO-A binding, high brain uptake, and fast and complete brain washout

Platelet aggregation inhibitor

Platelet aggregation inhibitor

Natural inhibitor of Wnt signaling, modulating β-catenin-dependent transcription

Natural cytotoxic withanolide antitumor agent, inducing apoptosis by decreasing mitochondrial membrane potential and elevating the Bax/Bcl-2 protein expression ratio

Natural flavonoidal alkaloid from the sea-grass Phyllosphadix iwatensis

Novel photoswitchable inhibitor of human dihydrofolate reductase

Novel photoswitchable sphingolipid probe

Novel porphyrazine-based photodynamic anti-cancer agent, inducing immunogenic cell death

Novel porphyrazine-based photodynamic anti-cancer agent, inducing immunogenic cell death

Novel photoswitchable sphingolipid probe, reversibly controlled S1P3-dependent pain hypersensitivity in mice and uniquely suited for the study of S1P biology in cultured cells and in vivo

Functionalized photoswitchable cereblon ligand for Degraders

Novel photocontrol inhibitor of the voltage-gated proton channel Hv1

Novel potent photoswitchable antagonist for a precise spatiotemporal control of β2-adrenoceptors

Novel photoswitchable BET bromodomain Degrader (PHOTAC)

Inducer of platelet aggregation, playing a role in cellular signal transduction and possibly in cell growth control and carcinogenesis

Sulindac derivative with promising anticancer activities

Potent antagonist of (H1N1)pdm09 infection, markedly suppressing cytopathic effects and attenuating viral gene expression in (H1N1)pdm09-infected MDCK cells

Natural anti-tumor agent, showing strong apoptotic anticancer effects against platinum-resistant solid cancers

Novel GPR173 agonist, promoting osteoblastic differentiation of MC3T3-E1 cells. stimulating mRNAs encoding hypothalamo-pituitary-gonadal hormones

Novel neuropeptide, protecting human brain vascular endothelial cells against oxygen-glucose deprivation/reoxygenation (OGD/R)-induced inflammation and permeability, significantly ameliorating HFD-induced obesity and fatty liver, regulating pituitary gona

Novel selective α-syn ligand, exhibited the promising binding characteristics for α-syn aggregates (Ki = 0.52 nM)

Blocker of dsRNA-induced IRF3 nuclear translocation and homodimerization; Inhibitor of lipopolysaccharide-mediated Toll-like receptor-4 signaling; Inhibitor of human pancreatic cancer

Inhibitor of internalization of cell surface receptors and tyrosine phosphatases, with no effect on tyrosine kinase