1,2-Linolein-3-caprylin is an acylglycerol.

1,2-Laurin-3-palmitin is an acylglycerol.

1,2-Eicosapentaenoin-3-docosahexaenoin is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

1,2-Butyrin-3-stearin is an acylglycerol.

1,2-Butyrin-3-linolein is an acylglycerol.

1,2-Arachidin-3-stearin is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

1,1-Dimethoxyhexadecane is an ether lipid. Ether lipids are mainly found in cell membranes.

1,10-Bis(methylsulfinyl)decane (Compound IIf) is a decamethonium analogue and is a non-electrolytic sulfoxide compound. 1,10-Bis(methylsulfinyl)decane has low lethal (LD50 >37.5 mg/kg) effect in mice and neuromuscular blocking (ED50 >7 mg/kg) effects in cat.

1-(2-(But-3-yn-1-yloxy)ethoxy)-6-chlorohexane is a PROTAC linker that can be used in the synthesis of PROTACs.

(S,S,S)-AHPC-PEG2-NH2 is an isomer of Compound 15b. Compound 15b is a conjugate of a VHL ligand and linker. Compound 15b can be used to synthesize PROTAC. Compound 15b can be used in leukemia research.

(S,S)-SARM1-IN-9 (Compound MY-13A) is a stereoselective SARM1 inhibitor with covalent binding properties. (S,S)-SARM1-IN-9 covalently modifies Cys311 in the autoregulatory ARM domain of wild-type SARM1, thereby blocking NADase activity, without inhibiting the SARM1C311A or SARM1C311S mutants. (S,S)-SARM1-IN-9 blocks vacor- and vincristine-induced axon degeneration in primary rodent dorsal root ganglion neurons. (S,S)-SARM1-IN-9 can be used for research on axon degeneration-dependent neurological disorders, including chemotherapy-induced peripheral neuropathy.

(S,S) Bisoleoyl-lysobisphosphatidic acid is a lysobisphosphatidic acid (LBPA). LBPA plays a role in modulating the cholesterol flux through endosomes.

(S,R,S,R)-AHPC-Me-CO-C7-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S,R)-AHPC-Me based VHL ligand and a linker used in PROTAC technology. (S,R,S,R)-AHPC-Me-CO-C7-N3 can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-28.

(S,R,S)-BBO-11818 (compound 59) is an inhibitor of KRAS that can be used in the research of cancer.

(S,R,S)-AHPC-Me-NHBoc is an E3 ubiquitin ligase VHL ligand used to recruit the VHL protein. (S,R,S)-AHPC-Me-NHBoc can be linked to a target protein ligand via a linker to form a PROTAC.

(S,R,S)-AHPC-Me-amide-C-O-PEG2-COOH is an E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-Me-amide-C-O-PEG2-COOH can be used for synthesis of PROTACs.

(S,R,S)-AHPC-CO-PEG3-NHBoc is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize PROTAC G9a/GLP degrader 1. PROTAC G9a/GLP degrader 1 is a potent G9a/GLP PROTAC degrader with anti-cancer activity.

(S,R,S)-AHPC-Bromooctanoic acid is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC and the corresponding linker. (S,R,S)-AHPC-Bromooctanoic acid can serve as VHL (von Hippel-Lindau) ligand to recruit the VHL protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

(S)-Oxybutynin is a pharmaceutical intermediate. (S)-Oxybutynin can synthesize antifungal agents.

(S)-LY-41, R-enantiomer of LY-41, is 2-Sminotetralin derivative and 8-OH-DPAT analogue. (S)-LY-41 is a potent and selective 5-HT1A receptor agonist. (S)-LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015). (S)-LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (S)-LY-41 can induce the 5-HT behavioral syndrome. (S)-LY-41can be used for the research of neurological disease, such as depression and anxiety.

(S)-JQ-35-Boc is a BRD4 ligand. (S)-JQ-35-Boc can be used to synthesize BRD4 degrader RAJQ14. RAJQ14 can be used for cancer research.

(S)-IP-DK143 is a polymeric micellar formulation. (S)-IP-DK143 inhibits the proliferation of cervical cancer cells, induces ROS-mediated apoptosis, and triggers mitochondrial dysfunction. (S)-IP-DK143 activates the p38 MAPK signaling pathway in cervical cancer cells, increases the phosphorylation level of p38, and slightly reduces the phosphorylation level of ERK. (S)-IP-DK143 can be used for the research of cervical cancer.

(S)-Glutarimide-amide-Py-piperidine-CHO is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

(S)-Bleximenib (Compound 28) ((S)-JNJ-75276617) is an isoform of Bleximenib. (S)-Bleximenib shows an IC50 greater than 1 μM in the MEIS1 mRNA expression assay. (S)-Bleximenib can be used in the research of acute myeloid leukemia.

(S)-5-HT2CR agonist 1 (Compound (S)-16k) is selective 5-HT2CR agonist, with an EC50 of 14 nM. FXa-IN-2 can be used in the research of hyperlocomotion.

(S)-2-Ketodoxapram ((S)-AHR 5955) is a metabolite of Doxapram. Doxapram is a respiratory stimulant[1][2].

(rel)-PRT062607 ((rel)-P505-15) is the relative configuration of PRT062607. PRT062607 is a highly selective inhibitor of Syk kinase, with an IC50 value of 1-2 nM, and is more than 80 times less potent against Fgr, Lyn, FAK, Pyk2, and Zap70.

(rel)-Nutlin carboxylic acid is the Nutlin 3-based MDM2 ligand. (rel)-Nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTAC.

(Rac)-UCB-J (Compound 23) is a ligand for synaptic vesicle protein 2A (SV2A), with a pIC50 value of 8.2. (Rac)-UCB-J can be used as a PET tracer for SV2A to assist in the diagnosis of epilepsy research.

(Rac)-Opnurasib ((Rac)-JDQ-443; (Rac)-NVP-JDQ443) is the levorotomer of Opnurasib. Opnurasib is an orally active, potent, selective, and covalent KRAS G12C inhibitor (extracted from patent WO2021120890A1). Opnurasib shows antitumor activity.