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Cat. No. Product Name Field of Application Chemical Structure
DC79886 (2S)-2-Amino-5-(2-amino-5-hydro-5-methyl-4-imi-dazolon-1-yl)pentanoic acid
(2S)-2-Amino-5-(2-amino-5-hydro-5-methyl-4-imi-dazolon-1-yl)pentanoic acid is an amino acid derivative.
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DC79885 (2R,3S,4R,5R)-GlcAc-GlcA
(2R,3S,4R,5R)-GlcAc-GlcA is a hexose derivative that can be used in the synthesis of ADC linkers.
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DC79884 (25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oyl-CoA
(25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oyl-CoA is a nucleoside metabolite.
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DC79883 (25R)-3Alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA
(25R)-3Alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA is a coenzyme A derivative.
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DC79882 (21R)-Argatroban
(21R)-Argatroban is a diastereoisomer of Argatroban. (21R)-Argatroban is also an inhibitor of thrombin with anticoagulant activity. (21R)-Argatroban can be used for research related to anticoagulation.
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DC79881 (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride
(2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride (compound 1AA) is a SETBP1 inhibitor that disrupts the interaction between SETBP1 and XPO1. (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride inhibits colony formation, induces differentiation/cytotoxicity, and downregulates the transcription of Setbpl target genes. (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride improves survival and reduces the spleen size of leukemic mice. (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride can be used for myeloid neoplasms and solid tumors research.
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DC79880 (1S,3S)-3-Hydroxycyclopentane carboxylic acid benzyl ester
(1S,3S)-3-Hydroxycyclopentane carboxylic acid benzyl ester ((1S,3S)-Benzyl-3-hydroxycyclopentanecarboxylate) is a synthetic intermediate. (1S,3S)-3-Hydroxycyclopentane carboxylic acid benzyl ester is useful for pharmaceutical synthesis.
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DC79879 (1R,9S)-Dxd
(1R,9S)-Dxd is an isomer of (Dxd). (1R,9S)-Dxd is an ADC payload that can be used in the synthesis of ADCs (antibody-drug conjugates).
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DC79878 (1R,9R)-rel-Exatecan
(1R,9R)-rel-Exatecan is a L-Dp derivative. (1R,9R)-rel-Exatecan can be produced by the cleavage of L-Dp (a drug-linker) under cellular conditions.
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DC79877 (1R)-KRAS inhibitor-24
(1R)-KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM for KRas G12V, KRas WT and KRas G12R.
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DC79876 (±)-U-50488
(±)-U-50488 ((±)-trans-(1R,2R)-U-50488) is a selective kappa opioid receptor agonist. (±)-U-50488 can improve symptoms related to status epilepticus, but has no significant effect on spontaneous seizure episodes. (±)-U-50488 can be used for research of epilepsy.
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DC79875 (±)-Homoproline
(±)-Homoproline (2-Pyrrolidineacetic acid) is the precursor for the biosynthesis of Tussilagine and Isotussilagine. (±)-Homoproline can be used in neurological research.
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DC79874 (+)-trans-Limonene oxide
(+)-trans-Limonene oxide is an antimicrobial essential oil component with activity against Staphylococcus aureus. (+)-trans-Limonene oxide acts as a selective agent for drug-resistant bacterial mutants without increasing the mutation frequency of Staphylococcus aureus USA300. (+)-trans-Limonene oxide can be used in studies of Staphylococcus aureus infection.
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DC79873 (+)-Sclareol oxide
(+)-Sclareol oxide is a compound that can be isolated from essential oils of Salvia sclarea. (+)-Sclareol oxide can be used in synthesis of puupehenone-related bioactive metabolites.
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DC79872 (+)-Adlumine
(+)-Adlumine (O-Methylcorledine) is an alkaloid derivative found in Corydalis ledebouriana.
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DC79871 (-)-P7C3-S243
(-)-P7C3-S243 is an orally active, blood-brain barrier permeable neuroprotective agent. (-)-P7C3-S243 binds to μ-opioid Receptor and TSPO. (-)-P7C3-S243 inhibits the premature apoptosis death of newborn hippocampal neurons, protects mature nigral dopaminergic neurons, promotes neuronal survival and prevents cognitive impairment. (-)-P7C3-S243 ameliorates depression-like behaviors in rat models. (-)-P7C3-S243 is applicable to research related to Parkinson's disease and Alzheimer's disease.
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DC79870 (-)-IHCH7041
(-)-IHCH7041 (Compound (-)-(S)-I-10) is a selective and orally active dopamine D2 receptor agonist with a Ki of 22.44 nM. (-)-IHCH7041 can activate Gαi1 protein and β-arrestin2 signaling pathway with EC50 values of 1.38 and 2.75 nM. (-)-IHCH7041 can improve cognitive impairment and memory capacity. (-)-IHCH7041 can be used for the research of neurological disease, such as Alzheimer's disease.
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DC77926 Litenimod sodium
Litenimod sodium is potent type B agonist of toll Like receptor 9 (TLR9), triggering both innate and adaptive immune response.
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DC77925 Lexaptepid Pegol
Lexaptepid Pegol is a pegylated structured L-oligoribonucleotide. It binds and inhibits hepcidin.
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DC77924 Lexaptepid Pegol sodium
Lexaptepid Pegol sodium is a pegylated structured L-oligoribonucleotide. It binds and inhibits hepcidin.
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DC77923 ISIS 1082
ISIS 1082 is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
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DC77922 ISIS 1082 sodium
ISIS 1082 sodium is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
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DC77921 IGFIIR aptamer sodium
IGFIIR aptamer sodium is an IGFIIR-specific aptamer that can be potentially used as a targeting ligand for the treatment and diagnosis of liver fibrosis.
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DC77920 MA191
MA191 is a FLT3 PROTAC degrader. MA191 abrogates FLT3 inhibitor resistance from rebound activation of mitogen-activated kinases. MA191 mediates rapid FLT3-ITD degradation through a mechanism requiring VHL, neddylation, and BIM. MA191 reduces FLT3-ITD levels before inducing apoptosis. MA191 halts AML cell proliferation in Danio rerio. MA191 can be used for the study of acute myeloid leukemia (AML).
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DC77919 2-Chloro-2′-deoxyadenosine monophosphate
2-Chloro-2′-deoxyadenosine monophosphate is an anticoronavirus agent. It exhibits significant inhibitory effects against wild-type novel coronavirus, novel coronavirus variants (Beta, Delta, and Omicron strains), and other coronaviruses such as human coronavirus 229E, human coronavirus OC43, human coronavirus NL63, and mouse coronavirus MHV.
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DC77918 (S,S,S)-VH032-cyclopropane-F-C4-aldehyde
(S,S,S)-VH032-cyclopropane-F-C4-aldehyde is an E3 ligase ligand-linker conjugate used in the synthesis of PROTAC cis-VZ185.
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DC77917 MRC-G-001
MRC-G-001 is a Genipin derivative with an IC50 of 117 μM against A549 cancer cells. MRC-G-001 inhibits the phosphorylation of EGFR, JAK1, and STAT3, and modulates epithelial-mesenchymal transition (EMT)-related protein expression, thereby attenuating cell migration and invasion. MRC-G-001 induces cell cycle arrest and cell apoptosis. MRC-G-001 can be used for the study of cancers such as non-small-cell lung cancer.
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DC77916 IAN-15B
IAN-15B has high selectivity and potent ST6GAL1 inhibitors (IC50 = 3.3 μM). IAN-15B has significant anti migratory and anti angiogenic effects. IAN-15B can be used in the research of cancer such as breast cancer.
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DC77915 PBD dimer-4
PBD dimer-4 (Compound 7) is a C1-subsitituted PBD dimer. PBD dimer-4 has high DNA-binding affinity, DNA cross-linking ability and potent cytotoxicity against MDA-MB-231 cells (IC50: 236 nM). PBD dimer-4 can be used as a payload of ADC Loncastuximab tesirine to treat several different cancer types.
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DC77914 LA-419
LA-419 is an orally active nitric oxide (NO) donor. LA-419 can significantly reduce the amount of fecal worm eggs excreted, shorten the duration of egg excretion, and also decrease the number of larvae in the lungs and the number of parasitic females in the intestines in mice infected with S. venezuelensis. LA-419 can reduce the formation of atherosclerosis in apolipoprotein E-deficient mice. LA-419 can be used for the researches of infection and cardiovascular disease.
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