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Cat. No. Product Name Field of Application Chemical Structure
DC72584 M47 Featured
M47 is a small molecule that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer.
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DC73063 MU-UNMC-2 Featured
MU-UNMC-2 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 1.72 uM in human bronchial epithelial cells.
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DC73397 BPRCX807
BPRCX807 (BPRCX-807) is a highly selective and potent CXCR4 antagonist with binding IC50 of 40.4 nM and EC50 of 48.1 nM for cell-mobility activity in the chemotaxis assays, inhibits CXCL12-mediated cell signaling pathway.
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DC73396 BPRCX714
BPRCX714 (BPRCX 714) is a highly selective and potent CXCR4 antagonist with binding IC50 of 34.2 nM, effectively inhibits CXCL12-induced movement of CCRF-CEM cells with EC50 of 13.7 nM.
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DC31451 CCS-1477(CBP-IN-1) Featured
CCS-1477 is a potent and selective p300/CBP bromodomain inhibitor, is targeted & differentiated from BET inhibitors in prostate cancer cell lines in vitro. Combination of CCS1477 & JQ1 resulted in a highly synergistic inhibitory effect on proliferation in normal 22Rv1 cells. Global gene expression analysis revealed significantly fewer altered genes after CCS1477 (27 up, 119 down) compared to JQ1 (196 up, 655 down).
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DC7723 OTS-964 Featured
OTS964 is a novel TOPK(T–lymphokine-activated killer cell–originated protein kinase) inhibitor.
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DC42537 ALC-0315 Featured
ALC-0315 is an ionisable aminolipid that used for mRNA compaction and aids mRNA cellular delivery. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles.
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DC60898 3-Hydroxycholesta-5,24-dien-7-one; 3β-form, Ac Featured
DC60897 Cholest-7-en-3-ol,acetate, (3b)- (9CI) Featured
DC60896 7,8-Didehydrocholesterol Acetate Featured
DC60895 7-p-Toluenesulfonylhydrazide Cholesterol 3-Acetate Featured
DC60894 7-Oxo Cholesterol 3-Acetate Featured
DC60893 3-Keto Cholesterol Featured
DC60892 7-Keto Cholesterol Featured
DC60891 4-Methyl-cholesterol Featured
DC43955 4α-Methylcholesterol Featured
4α-Methylcholesterol is a Cholesterol derivative. 4α-Methylcholesterol can oxidize 3-hydroxy steroid, with the apparent Km of 12.6 μM.
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DC60890 22a-Hydroxy Cholesterol Featured
DC67628 NMDC-Cholesterol Featured
DC21557 RB-011 Featured
A small molecule that disrupt 14-3-3 dimers at low micromolar concentrations and induce rapid down-regulation of Raf-MAPK and PI3K-Akt signaling in Jurkat cells.
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DC60889 3β-Acetoxy-5α-cholesta-7,24-diene Featured
DC60887 (3β,5α)-Cholesta-8(14),24-dien-3-ol Featured
DC60888 DESMOSTEROL ACETATE Featured
DC60881 5alpha-cholestanyl-(3beta)-hydrogen sulfate Featured
DC36443 DC-Chol hydrochloride Featured
DC-Chol hydrochloride is a cationic lipid. DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner. DC-Chol hydrochloride induces the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. DC-Chol hydrochloride can enhance the body's immune response to antigens. DC-Chol hydrochloride is used as a gene delivery vector. DC-Chol hydrochloride can be used in research in areas such as hepatitis B vaccines to improve vaccine immunity.
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DC60885 5alpha-Cholest-7-en-3beta-ol Featured
DC60886 5-alpha-cholest-7,24-dien-3beta-ol Featured
DC45677 5α-Cholesta-7,24-dien-3β-ol Featured
5α-Cholesta-7,24-dien-3β-ol, a sterol, can be found in hamster cauda epididymal mature spermatozoa.
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DC32956 Desmosterol Featured
Desmosterol is an endogenous agonist of RORgamma; Intermediate in the synthesis of cholesterol.
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DC12188 Lathosterol Featured
Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis.
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DC12199 Cholestenone Featured
Cholestenone is the intermediate oxidation product of cholesterol.
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