A selective inhibitor of c-Met kinase

Selective and potent antagonist of the transient receptor potential melastatin-8 (TRPM8) channel

5-HT1A/1B serotonin receptor antagonist; β3-adrenoceptor antagonist

Highly selective D2 dopamine receptor antagonist

Potent P2X7 antagonist blocking BzATP-evoked calcium influx

Potent in vitro and in vivo inhibitor of fatty acid amide hydrolase (FAAH)

Novel Inhibitor of Bacterial Cytokinesis, inhibiting FtsZ

Calcium entry blocker, also being used as the precursor for radiolabelling emopamil

Novel reversible inhibitor of autophagic flux, preventing Stx17 loading onto autophagosomes and blocking autophagosome-lysosome fusion without any effect on lysosomal properties or on endocytosis mediated degradation of EGF receptor

Glucocorticosteroid; Antipsoriatic agent

Novel inhibitor of canonical Wnt signaling

An anticholinergic drug used in patients to reduce the side effects of antipsychotic treatment and a second-line drug for the treatment of Parkinson's disease

Anti-inflammatory and analgesic agent

Prodrug of indomethacin, nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug (DMARD)

Inhibitor of the parasympathetic nervous system actions

Novel specific Inhibitor of histone acetyltransferase

The first small molecule, S1P2 selective agonist reported

Novel positive modulator of GABAA receptors