Cat. No. | Product Name | Field of Application | Chemical Structure |
---|---|---|---|
DC9583 | Oglemilast Featured |
Oglemilast(GRC3886) is a potent PDE4 inhibitor, under clinical studies in the treatment of allergen-induced asthma.
More description
|
![]() |
DC11905 | Opiranserin Featured |
Opiranserin (VVZ-149, VVZ-000149) is a potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM), purine P2X3 receptor antagonist (IC50=0.87 uM) and serotonin 5-HT2A receptor antagonist (IC50=1.3 uM).
More description
|
![]() |
DC7456 | LX1606 Hippurate Featured |
LX1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.
More description
|
![]() |
DC8882 | Bitopertin Featured |
Bitopertin, also known as RG1678, is a potent and selective inhibitor of GlyT1 with an EC50 of 30nM.
More description
|
![]() |
DC11495 | Allitinib Featured |
Allitinib (AST-1306, ALS1306)) is a novel potent, selective irreversible EGFR and HER2 inhibitor with IC50 of 0.5 and 3 nM in cell-free assays.
More description
|
![]() |
DC7335 | URB-597 Featured |
URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets.
More description
|
![]() |
DC7016 | JNJ40411813 Featured |
For the detailed information of JNJ40411813, the solubility of JNJ40411813 in water, the solubility of JNJ40411813 in DMSO, the solubility of JNJ40411813 in PBS buffer, the animal experiment (test) of JNJ40411813, the cell expriment (test) of JNJ40411813, the in vivo, in vitro and clinical trial test of JNJ40411813, the EC50, IC50,and Affinity of JNJ40411813, Please contact DC Chemicals..
More description
|
![]() |
DC1501 | Everolimus Featured |
Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM.
More description
|
![]() |
DC8115 | Vancomycin hydrochloride Featured |
Vancomycin hydrochloride in stock,price: 500 USD/100mg. 0
More description
|
![]() |
DC10301 | Emodepside Featured |
Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.
More description
|
![]() |
DC1057 | Fidaxomicin (Dificid) Featured |
Fidaxomicin, is an antibiotic that belongs to the class of macrocylic antibiotics.
More description
|
![]() |
DC11524 | Mavacamten(MYK-461) Featured |
Mavacamten(MYK-461)is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain.
More description
|
![]() |
DC1084 | ZM447439 (ZM-447439) Featured |
ZM-447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively.
More description
|
![]() |
DC9299 | GRA Ex-25 Featured |
GRA Ex-25 is an orally active human glucagon receptor antagonist in a transgenic murine pharmacodynamic model at 10 and 30 mpk.
More description
|
![]() |
DC7419 | GNE-7915 Featured |
GNE-7915 is a highly potent, selective, and brain-penetrable LRRK2 small molecule inhibitor with IC50 of 9 nM in cellular LRRK2 assay; > 100 fold selectivity against a panel of 187 kianses(Ki).
More description
|
![]() |
DC7137 | Filgotinib(GLPG0634) Featured |
Filgotinib (GLPG0634) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib can effectively inhibit the activities of JAK1, JAK2, JAK3 and TYK2 with IC50 values of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib can be used in the study of rheumatoid arthritis and inflammatory bowel disease.
More description
|
![]() |
DC9595 | E-4031 Featured |
E-4031 is a benzenesulfonamide antiarrhythmic agent; blocks the ATP-sensitive potassium channel.
More description
|
![]() |
DC9826 | BCTC Featured |
BCTC is a potent and specific inhibitor of transient receptor potential cation channel subfamily M member 8 (TRPM8) in prostate cancer (PCa) DU145 cells.
More description
|
![]() |
DC8840 | CB-5083 Featured |
CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models .
More description
|
![]() |
DC8168 | Peficitinib(ASP015K,JNJ-54781532) Featured |
Peficitinib(ASP015K,JNJ-54781532) is a novel potent JAK inhibitor, which demonstrated potent efficacy in adjuvant-induced arthritis model in rats.
More description
|
![]() |
DC9738 | GSK2881078 Featured |
GSK-2881078 is an orally active and nonsteroidal selective androgen receptor modulator (SARM) which act as partial AR agonists in androgenic tissues while mainly as complete AR agonists in synthetic metabolic tissues,induces AR-mediated transcriptional activation in PC3(AR)2 cells (EC50 = 3.99 nM) and the effect can be inhibited by the non-steroidal AR antagonist Bicalutamide. GSK-2881078 can be used in research of muscle weakness and cachexia associated with both chronic and acute illness.
More description
|
![]() |
DC7633 | Ligandrol (VK5211, LGD-4033) Featured |
Ligandrol (LGD-4033) is a novel nonsteroidal, oral SARM that binds to androgen receptor with high affinity (Ki of 1 nM) and selectivity.
More description
|
![]() |
DC8248 | Ostarine(MK-2286) Featured |
Ostarine (MK-2866) is a selective androgen receptor modulator (SARMs) that regulates cardiomyocyte function, improves bone healing, regulates uterine function, and influences muscle tissue metabolism.
More description
|
![]() |
DC7367 | AZ-960 Featured |
AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, 3-fold selectivity of AZ960 for JAK2 over JAK3.
More description
|
![]() |
DC4226 | Moxifloxacin hydrochloride Featured |
Moxifloxacin(Avelox, Avalox) is a fourth generation synthetic fluoroquinolone antibacterial agent.
More description
|
![]() |
DC7058 | Amprenavir Featured |
Amprenavir (Agenerase) is a HIV protease inhibitor(Ki=0.6 nM) used to treat HIV infection.
More description
|
![]() |
DC7276 | Saracatinib (AZD0530) Featured |
Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q).
More description
|
![]() |
DC10925 | SAR-100842 Featured |
SAR-100842 (SAR100842) is a potent, selective, orally available antagonist of the Lysophosphatidic Acid 1 Receptor (LPA1 receptor) with IC50 of 31 nM in β-arrestin assays.
More description
|
![]() |
DC11726 | Milademetan Featured |
Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest, senescence and apoptosis.
More description
|
![]() |
DC7694 | BAF312 (Siponimod) Featured |
BAF312 is a potent and selective agonist of S1P with EC50 value of 0.39nM for S1P1 receptors and 0.98nM for S1P5 receptors, respectively
More description
|
![]() |