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GeA-69

  Cat. No.:  DC11504   Featured
Chemical Structure
2143475-98-1
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More than 5000 active chemicals with high quality for research!
Field of application
GeA-69(GeA69) is a potent, selective, allosteric, cell-active PARP14 macrodomain 2 (MD2) inhibitor with Kd of 0.86 uM in ITC assays.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2143475-98-1
Chemical Name: N-(2-(9H-carbazol-1-yl)phenyl)acetamide
Synonyms: GeA69
SMILES: C(NC1=CC=CC=C1C1=CC=CC2C3=C(NC1=2)C=CC=C3)(=O)C
Formula: C20H16N2O
M.Wt: 300.361
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. Schuller M, et al. Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14. ACS Chem Biol. 2017 Nov 17;12(11):2866-2874.
Description: GeA-69 is a selective, highly cell permeable allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2, with a Kd of 2.1 µM[1].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
Cat. No. Product name Field of application
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