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Minoxidil sulfate

  Cat. No.:  DC41224   Featured
Chemical Structure
83701-22-8
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More than 5000 active chemicals with high quality for research!
Field of application
Minoxidil sulfate, a potent and ATP-sensitive K+ channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 83701-22-8
Chemical Name: minoxidil sulfate
Synonyms: minoxidil sulfate;minoxidilsulfateester;6-(1-PIPERIDINYL)-2,4-PYRIMIDINEDIAMINE-3-OXIDE SULFATE;MINOXIDIL SULPHATE;U-58838;MINOXIDIL SUFATE ETHYLATED;(2,6-diamino-4-piperidin-1-ylpyrimidin-1-ium-1-yl) sulfate;2,6-Diamino-4-(piperidin-1-yl)-pyrimidine 1-oxide sulfate;6-(1-Piperidinyl)-2,4-pyrimidinediamine-3-oxide sulfate
SMILES: C1CCN(CC1)C2=CC(=N)N(C(=N)N2)OS(=O)(=O)O
Formula: C9H15N5O4S
M.Wt: 289.31
Purity: >98%
Sotrage: Powder-20°C3 yearsIn solvent-80°C6 months-20°C1 month
MSDS
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MSDS_24237_DC41224_83701-22-8
COA
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Cat. No. Product name Field of application
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DC70574 Lu AA41178 Lu AA41178 is a potent, pan-selective Kv7.2-7.5 opener with EC50 of 1.5, 0.6 20.5, and 37.0 uM for Kv7.2, Kv7.2/7.3, Kv7.4 and Kv7.5, respectively.Lu AA41178 displays no activity at Kv7.1 channels, has no potentiating impact on currents through GABAA ion channels, and a clean off-target profile against common cardiac ion channels.Lu AA41178 significantly increased the seizure thresholds in mice, demonstrating anticonvulsant efficacy in the maximum electroshock seizure threshold test and PTZ seizure threshold test.Lu AA41178 demonstrated antipsychotic-like activity by reducing amphetamine-induced hyperlocomotion in mice as well as lowering conditioned avoidance responses in rats, significantly reduced immobility in mouse model with antidepressant predictivity.
DC70426 GAT1508 GAT1508 (GAT-1508) is a potent, specific activator for brain-expressed GIRK1/2 channels (EC50=75 nM), specifically activates the brain GIRK1/2 over the cardiac GIRK1/4; GAT1508 is an allosteric modulator of channel–phosphatidylinositol 4,5-bisphosphate interactions. GAT1508 effectively extinguished conditioned fear in rodents and lacked cardiac and behavioral side effects, suggesting its potential for use in pharmacotherapy for post-traumatic stress disorder.
DC70327 CTIBD CTIBD is a novel potent activator of the BKCa channel with EC50 of 3.9 uM.CTIBD showed significantly higher potency compared with three other known BKCa activators: NS 1619, NS 11021, and rottlerin.CTIBD induced a reversible potentiation of macroscopic outward currents of the BKCa channel, CTIBD activates both rSlo/rβ1 and rSlo/rβ4 coexpressed channels mainly by decreasing the closing rate of the channel.CTIBD concentration-dependently reduced ACh-induced contractions in isolated rat urinary bladder strips. CTIBD effectively restored frequent voiding contraction and lowered voiding volume without affecting other bladder function parameters in acetic acid-induced overactive bladder (OAB) model (i.p. 20 mg/kg).
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DC41224 Minoxidil sulfate Minoxidil sulfate, a potent and ATP-sensitive K+ channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo.
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