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SCR130

  Cat. No.:  DC45555   Featured
Chemical Structure
2377858-38-1
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More than 5000 active chemicals with high quality for research!
Field of application
SCR130 is a novel DNA repair inhibitor with IC50s of 14 μM in Reh cells and 2 μM in Nalm6 cells. SCR130 specifically inhibits DNA Ligase IV‐mediated joining with minimal or no effect on Ligase III and Ligase I mediated joining.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2377858-38-1
Chemical Name: SCR130
Synonyms: SCR130;s9775;2,4-Bis(4-chlorophenyl)-8-sulfanylidene-1,7,9-triazaspiro[4.5]dec-1-ene-6,10-dione;G18284;G18284;CS-0188739;CS-0188739;HY-139297;HY-139297;DA-57746;DA-57746;2377858-38-1;2377858-38-1;AKOS040759695;AKOS040759695;EX-A5323;EX-A5323;MS-27299;MS-27299
SMILES: ClC1C=CC(=CC=1)C1CC(C2C=CC(=CC=2)Cl)=NC21C(NC(NC2=O)=S)=O
Formula: C19H13Cl2N3O2S
M.Wt: 418.296420812607
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC45555 SCR130 SCR130 is a novel DNA repair inhibitor with IC50s of 14 μM in Reh cells and 2 μM in Nalm6 cells. SCR130 specifically inhibits DNA Ligase IV‐mediated joining with minimal or no effect on Ligase III and Ligase I mediated joining.
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DC42292 DENV-IN-2 DENV-IN-2 is a potent dengue viral replication extracted from patent WO2018215315A1, compound 6AB, has an EC50 of 0.016 nM. DENV-IN-2 shows high potent activity against all four serotypes of the Dengue virus with EC50s ranging from 0.013 to 0.029 nM.
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