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DC65200 | DKI5 Featured |
DKI5, also known as (E)-N’-benzylidenehydrazinecarbothiohydrazide, is a LOX-1 inhibitor with an IC50 value of 22.5 μM. DKI5 strongly inhibits lipid peroxidation.
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DC65194 | HUN39963 Featured |
HUN39963, also known as LDH-IN-2 is an inhibitor of glycolate oxidase. This compound was first reported in J Med Chem.
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DC65198 | VUN28691 Featured |
VUN28691, also known as p38α inhibitor 3, is a p38α inhibitor for treatment of p38-α kinase-mediated conditions.
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DC65197 | GSK-3β Inhibitor II Featured |
GSK3β Inhibitor II, also known as KIN 001-042, also known as GSK-3β Inhibitor II, is a GSK-3β inhibitor.
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DC65196 | CUN11141 Featured |
CUN11141, also known as BRD4 Inhibitor-20, is a potent orally active bromodomain protein 4 (BRD4) inhibitor. It can be used for the research of kinds of cancer, such as colon cancer.
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DC65195 | ZVN26391 Featured |
ZVN26391, also known as NLRP3-IN-10, is a IL-1β inhibitor for the treatment of inflammation and inflammation-related disease (neurogenic inflammation, Alzheimer disease, etc.).
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DC65193 | WAY-299838 Featured |
WAY-299838 is a useful chemical agent for chemical synthesis of hypoxia-inducible factor-1 inhibitor.
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DC65192 | RXN00442 Featured |
RXN00442, also known as EGFR-IN-11, is a fourth-generation EGFR-tyrosine kinase inhibitor (EGFR-TKI). This compound was first reported in Eur J Med Chem.
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DC65191 | WAY-658513 Featured |
WAY-658513 is a multiple kinase inhbitor. WAY658513 was shown to inhibit ROCK I, ERK2, GSK3, and PKA with Ki <1 μM.
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DC65190 | NSC321039 Featured |
NSC321039, also known as hMAO-B-IN-4, is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value of 0.067 μM.
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DC65189 | BDTX-1535 Featured |
BDTX-1535 is a potent, selective, brain penetrant and irreversible MasterKey inhibitor of EGFR mutations that expressed in glioblastoma multiforme (GBM) and intrinsic and acquired resistance EGFR mutations in non-small cell lung cancer (NSCLC).
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DC65188 | Moracin C Featured |
Moracin C is a phenolic compound isolated from Artocarpus heterophyllus. Moracin C suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages.
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DC9508 | CPPHA Featured |
CPPHA is a selective positive allosteric modulator of mGluR5 receptor.
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DC65187 | HHS-0701 Featured |
HHS-0701, a sulfur-triazole exchange (SuTEx) ligand, is a potent tyrosine-reactive prostaglandin reductase 2 (PTGR2) inhibitor. HHS-0701 blocks PTGR2 metabolism of the lipid substrate 15-Keto-PGE2.
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DC65186 | DCFH Featured |
DCFH, also known as 2',7'-dichlorodihydrofluorescein, is a fluororescent agent. It is a key chemcial for the dichlorofluorescin (DCFH) oxidation assay.
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DC65185 | AD-57 Featured |
AD-57, also known as KIRA 1, is an IRE1 inhibitor for cancer inflammation autoimmune disease therapy.
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DC65184 | WAY-640810 Featured |
WAY-640810 is a chemical agent which may alter the lifespan of a eukaryotic organism.
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DC65183 | WAY-313013 Featured |
WAY-313013 is a p38a Mitogen-Activated Protein Kinase inhibitor.
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DC40968 | LUN09945 Featured |
LUN09945 is a potent RETV804M kinase inhibitor. LUN09945 was first reported by Rebecca Newton et al (Compound 13, in ACS Med Chem Lett. 2020;11(4):497-505). This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature
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DC28661 | Cdc7-IN-7 Featured |
Cdc7-IN-7 (compound I-E) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-E. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle.
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DC65177 | 8-Azaadenosine Featured |
8-Azaadenosine is a potent ADAR1 inhibitor and an A-to-I editing inhibitor. 8-Azaadenosine blocks RNA editing and inhibits proliferation, 3D growth, invasion, and migration in thyroid cancer cells.
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DC60450 | ZW251 Featured |
ZW251 is an antibody drug conjugate (ADC) consisting of a topoisomerase l inhibitor payload conjugated to an antibody targeting Glypican-3(GPC3).
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DC65175 | CPD10000-A2 Featured |
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DC65174 | CPD1584-B3 HCl Featured |
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DC65172 | CPD2810-A4 Featured |
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DC65171 | 2-Isopropyl-4-methylpyridin-3-amine Featured |
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DC65169 | CPD2809-SM Featured |
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DC65166 | 2,6-Difluoro-3,5-dimethoxyaniline Featured |
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DC65165 | Allo-UDCA Featured |
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DC65164 | 6-(4-chlorobenzoyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one Featured |
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