Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC29050 | Fibrin Featured |
Fibrin, isolated from bovine blood, is an insoluble protein produced in response to bleeding. Fibrin is the major component of the blood clot and is used for coagulation.
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DC29057 | Mecamylamine hydrochloride Featured |
Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier.
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DC29074 | (R)-(+)-Atenolol Featured |
(R)-(+)-Atenolol is the less active enantiomer of the (R,S)-atenolol. (R,S)-atenolol is a β-adrenergic receptor antagonist.
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DC29101 | Ivachtin Featured |
Ivachtin (Caspase-3 Inhibitor VII; compound 7a) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor with an IC50 of 23 nM. Ivachtin has modest selectivity for the remaining caspases.
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DC11290 | QC-3611 Featured |
QC-3611 is a selective inhibitor of JARID1A/1B, which is a target existing in various tumors (JARID1A IC50 = 13 nM ;JARID1B IC50 = 2 nM). QC-3611 is promisingly to be used as an antineoplastic drug.
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DC29170 | L-Methionine sulfoxide Featured |
L-Methionine sulfoxide (H-Met(O)-OH), a metabolite of Methionine, induces M1/classical macrophage polarization, and modulates oxidative stress and purinergic signaling parameters.
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DC29172 | Obidoxime dichloride Featured |
Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated.
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DC29183 | Disodium succinate Featured |
Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
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DC29185 | 2-Acetamidophenol Featured |
Paracetamol (4-acetamidophenol). 2-Acetamidophenol is a promising analgesic and an anti-arthritic agent.
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DC29190 | m-PEG3-Amine Featured |
m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC29208 | m-PEG4-Amine Featured |
m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC29211 | m-PEG8-Amine Featured |
m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC29217 | N-Boc-diethanolamine Featured |
N-Boc-diethanolamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC3159 | Gemifioxacin Featured |
Gemifloxacin mesylate (trade name Factive, Oscient Pharmaceuticals) is an oral broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia.
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DC3161 | Prasugrel Featured |
A novel platelet inhibitor
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DC5144 | 1-Azakenpaullone Featured |
1-Azakenpaullone is a potent and ATP-competitive GSK-3β (glycogen synthase kinase-3β) inhibitor (IC₅₀ = 18 nM).
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DC7030 | SC-560 Featured |
SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors which includes celecoxib (Celebrex™) and rofecoxib (Vioxx™).
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DC9766 | LY3177833 Featured |
LY3177833 is a novel CDC7 inhibitor,CDC7/DBF4 IC50 = 3.3 nM, pMCM2 (S53) IC50 = 290 nM and IVTI TEC70 = 1.6 mcM.
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DC10675 | LY3200882 Featured |
LY3200882 is a novel, highly selective TGFβRI small molecule inhibitor.
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DC10712 | LY334370 Featured |
LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM.
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DC10926 | LY900009 Featured |
LY900009 (LY-900009) is an orally active small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.
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DC10715 | LYN-1604 Featured |
LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM).
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DC12034 | MA-0204 Featured |
MA-0204 is a potent, selective PPARδ modulator with good pharmacokinetic properties.
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DC20269 | mAChR-IN-1 Featured |
mAChR-IN-1 is a potent muscarinic cholinergic receptor(mAChR) antagonist with IC50 of 17 nM..
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DC7095 | W-7 hydrochloride Featured |
Calmodulin antagonist. Inhibits Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 μM) and myosin light chain kinase (IC50 = 51 μM).
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DC7159 | TPCA-1 Featured |
TPCA-1 is potent, selective inhibitor of IKK-2 (IC50 = 17.9 nM) that displays>22-fold selectivity over IKK-1 and > 550-fold selectivity over other kinases and enzymes.
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DC7272 | Rufinamide Featured |
Rufinamide(E 2080; CGP 33101; RUF 331) is a new antiepileptic agent that differs structurally from other antiepileptic drugs and is approved as adjunctive therapy for Lennox-Gastaut syndrome (LGS).
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DC7377 | BMY 7378 Featured |
BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3.
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DC10560 | MAK683 Featured |
MAK683 is a novel PRC2/EED inhibitor.
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DC7542 | BQ-788 Featured |
BQ-788 sodium salt is a potent, selective ETB receptor antagonist (IC50 = 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells); poorly inhibited the binding to ET A receptors in human neuroblastoma cell line SK-N-MC cells (IC(50), 1300 nM).
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