A broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM(biochemical assay), and 0.31 nM (cell function assay).

A bis-anthracycline and melanoma selective agent that demonstrates anti-melanoma activity at low nanomolar concentrations.

A biologically active natural product isolated from Streptomyces that has been shown to inhibit tumor cell migration.

A bioactive, specific small molecule that targets RNA of the expanded repeat (r(GGGGCC)exp) with Kd of 9.7 uM.

A benzophenone tetracarboxylic derivative that can improve the activity and stability of alkaline phosphatases from psychrophilic and mesophilic organisms..

A benzodiazepine inhibitor that directly interacts with RUNX1 and CBFβ, represses RUNX1/CBFβ-dependent transactivation in reporter assays.

A anti-HIV-1 compound that interferes with HIV-I integrase binding to viral DNA..

A angiotensin-converting enzyme (ACE) inhibitor for treatment of hypertension, heart failure, and after heart attacks..

A 4′-azidocytidine analogue that shows anti-HCV activity..

A 4′-azidocytidine analogue that shows anti-HCV activity..

A 385358 is a potent, selective, cell-permeable Bcl-XL inhibitor with Ki of 0.8 nM, displays >80-fold selectivity over Bcl-2 (Ki=64 nM).

A 2-cyanoaziridine derivative with antitumor activity in some types of cancer, including pancreatic, lung, breast, prostate, melanoma, and multiple myeloma.

8-O-Acetyl shanzhiside methyl ester (ND01) is an iridoid glucoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang.

7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR.

7-BIA is a small molecule 7-butoxy illudalic acid analog that targets receptor-type protein tyrosine phosphatase D (PTPRD, IC50=1-3 uM) with some specificity.

7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.

6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro.

6-Mercaptopurine Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.

6-Hydroxybentazon is a phase I metabolite of bentazone, and bentazone is a chemical for use in herbicides.

6-FABA (6-Fluoroanthranilic Acid) is a small-molecule inhibitor of MTB tryptophan synthesis that converts Mtb into a tryptophan auxotroph and restores the efficacy of a failed host defense.

6-Ethylthioinosine (6-ETI.

6-Dimethylaminopurine is a serine threonine protein kinase inhibitor. It inhibits the germinal vesicle breakdown and the meiotic maturation of oocytes.

5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification.

5-R-Rivaroxaban is (R) enantiomer of Rivaroxaban.

5-NITP (5-nitro-indolyl-2'-deoxyribose triphosphate) is a non-natural nucleotide that inhibits ribonucleotide reductase (hRR) with IC50 of 170 uM, demonstrates anti-cancer effects against leukemia cells by altering cell-cycle progression..

5-NIdR (5-nitro-indolyl-2'-deoxynucleoside) is a non-natural nucleotide produces cytostatic and cytotoxic effects against human leukemia cells by altering cell-cycle progression.

5MPN a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3.

5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors.

5'-GTP trisodium salt hydrate is an activator of the signal transducing G proteins and also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

5-bromoindole is an important pharmaceutical chemical intermediate and a potential inhibitor of glycogen synthase kinase 3 (GSK-3).