Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC73970 | DFTD |
DFTD is a time-dependent, reversible and covalent inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K) targeting of Cys-146, DFTD binds to the ATP binding site of eEF-2K.
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DC73969 | DFO-5 |
DFO-5 (Oseltamivir Epoxy Impurity) is an oseltamivir impurity.
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DC73968 | DDX3X helicase 86 |
DDX3X helicase 87 is a potent, selective and aller inhibitor of DDX3X helicase activity with IC50 of 7 nM, shows antiviral activity against DENV-2 and WNV with EC50 of 6.3 and 0.88 uM, respectively.
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DC73967 | DDX3X helicase 79 |
DDX3X helicase 79 is a potent, selective inhibitor of DDX3X helicase activity with IC50 of 5 nM, shows antiviral activity against DENV-2 and WNV with EC50 of 1.6 and 2.3 uM, respectively.
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DC73966 | DDX3X helicase 64 |
DDX3X helicase 64 is a potent, selective inhibitor of DDX3X helicase activity with IC50 of 0.14 μM, shows promising anti-HCV activity, with an EC50 of 0.2 μM and cytotoxicity of 86 μM.
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DC73965 | DDIT |
DDIT is a potent, non-toxic inhibitor of hyaluronan synthesis via targeting hyaluronan synthase (HAS), significantly suppresses the aggressiveness of triple-negative breast cancer cells grown in tissue culture.
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DC73964 | DC-SX029 |
DC-SX029 is a new small-molecule sorting nexin 10 (SNX10) inhibitor (KD=0.935 uM), blocks the SNX10-PIKfyve interaction, decreases TBK1/c-Rel signaling activation.
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DC73962 | Cytochalasin B |
Cytochalasin B is a cell-permeable mycotoxin that inhibits network formation by actin filaments, inhibits cell movement and induces nuclear extrusion.
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DC73960 | CW4142 |
CW4142 (CW 4142) is a small molecule SC4MOL inhibitor that enhances oligodendrocyte formation.
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DC73959 | CW3388 |
CW3388 (CW-3388, CW3388) is a potent, cell-active Δ8,7-sterol isomerase (EBP) inhibitor, shows near-maximal effects on oligodendrocyte formation at 110 nM.
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DC73958 | CU-76 |
CU-76 (cGAS inhibitor CU-76) is a small-molecule human cGAS (hcGAS) inhibitor with IC50 of 0.24 uM.
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DC73957 | CT-179 |
CT-179 is a small molecule inhibitor of protein transcription factor OLIG2 (Oligodendrocyte transcription factor 2), CT-179 is a putative disruptor of OLIG2 homodimerization.
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DC73956 | CRS0540 |
CRS0540 is a potent, selective PolC DNA polymerase inhibitor that has demonstrated good in vitro and in vivo activity against Listeria monocytogenes.
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DC73955 | CQ211 |
CQ211 is a potent, highly selective RIOK2 inhibitor with Kd of 6.1 nM, shows excellent selectivity to RIOK2 in both enzymatic and cellular assays.
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DC73954 | CPR1-B |
CPR1-B is a longer-acting phenylhexanamide mitofusin activator, increases mitochondrial motility in MFN2 T105M expressing mouse DRGs with EC50 of 3.3 nM (Emax=89%).
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DC73952 | Coproporphyrin III |
Coproporphyrin III is a diffusible small molecule porphyrin excreted by human-associated Propionibacterium spp., induces Staphylococcus aureus aggregation and biofilm formation, also induces S. aureus to form a plasma-independent surface-attached biofilm.
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DC73951 | CNS-11g |
CNS-11g is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core.
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DC73950 | CNS-11 |
CNS-11 is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core.
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DC73947 | Cl-NIO |
Cl-NIO is a potent, selective inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 1.3 uM, > 500-fold selectivity against arginase and endothelial nitric oxide synthase.
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DC73946 | CKi-6 |
CKi-6 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells.
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DC73945 | CKi-4 |
Creatine kinase inhibitor CKi-4 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.3 uM, depletes creatine phosphagen energetics in cells.
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DC73943 | Cimlanod |
Cimlanod is a second-generation nitroxyl (HNO) donor..
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DC73942 | CIB-3b |
CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
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DC73941 | CHD1Li 11 |
CHD1Li 11 (CHD1L inhibitor 11) is a small molecule inhibitor of chromodomain helicase DNA-binding protein 1 like (CHD1L) with IC50 of 4.57 uM.
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DC73940 | CC-410 |
CC-410 (CC410) is a potent, specific inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 1.6 uM (human NNMT).
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DC73939 | CBLC000 |
CBLC000 (CBL0100) is a small molecule histone chaperone FACT inhibitor, activates p53 and inhibits NF-κB with EC50 of 0.06 and 0.03 uM in cell-based p53 and NF-κB reporter assays, respecitvely.
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DC73938 | CBK034026C |
CBK034026C is a small molecule targeting metabolic vulnerabilities caused by N-acetyltransferase 2 (NAT2) activity, exhibits specific toxicity towards colorectal cancer (CRC) cells with high NAT2 activity.
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DC73937 | CB253 |
CB253 is a small molecule that selectively binds the hairpin form of r(G4C2)exp, inhibiting mechanisms that drive c9ALS/FTD pathobiology.
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DC73936 | CASK chemical probe 18 |
CASK chemical probe 18 is a highly potent and selective CASK inhibitor with IC50 of 22 nM.
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DC73935 | CARD8 activator CQ31 |
CARD8 activator CQ31 is a small molecule that selectively activates CARD8.
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