ATP dimagnesium (Adenosine 5'-triphosphate dimagnesium) is a central molecule in energy metabolism, driving cellular pumps and acting as a coenzyme. It also functions as an endogenous signaling molecule that modulates immune responses and activates the NLRP3 inflammasome, contributing to host defense during bacterial infections.

ABD0171 is a potent, irreversible, and selective inhibitor of aldehyde dehydrogenase 1A3 (ALDH1A3), with an IC50 of 0.34 µM using the physiological substrate all-trans-retinaldehyde (atRAL). It also inhibits ALDH1A2 and ALDH1A1 with IC50 of 0.79 µM and 6.6 µM, respectively. ABD0171 disrupts key oncogenic pathways in triple-negative breast cancer (TNBC) cells in vitro and exhibits robust antitumor and antimetastatic activity in vivo.

6K465 is a pyrimidine-based inhibitor of Aurora A, that reduces levels of c-MYC and N-MYC oncoproteins. It demonstrates compelling antitumor efficacy.

2-bromoethanol-d4 is the deuterated derivative of 2-bromoethanol. 2-bromoethanol is a cytotoxic alkylating agent.

1-Methyl-1,4-piperazine-d8 is the deuterated derivative of 1-methyl-piperazine.

(S)-Terazosin is a potent and selective antagonist of α-adrenoceptor with Ki values of 3.91 nM, 0.79 nM and 1.16 nM for α1a, α1b and α1d-adrenoceptor, respectively. It also has high-affinity for α2a, α2B and α2c-adrenoceptor with Ki values of 729 nM, 3.5 nM and 46.4 nM, respectively. It may prove to be a useful probe in understanding the functional role of subtypes of adrenoceptors in various tissues.

(D5)epichlorohydrin is the deuterated form of epichlorohydrin. Epichlorohydrin is a highly toxic industrial raw material with alkylating activity.

Trimecaine, a local neural blockade agent, has a strong depressant effect on the cerebral cortex and the ascending reticular formation of the brain stem.

Triglyceride OLO,sn (Compound 2) is a triglycerides that can be isolated from Dirca palustris.

SU-740 is a chalcone derivative with anti-ulcer activity.

Sporidesmolide III is a cyclodepsipeptide originally isolated from P. chartarum.

PSSI-51 is an orally active, peripherally selective inhibitor of succinyl-CoA:3-ketoacid-CoA transferase (SCOT). PSSI-51 inhibits SCOT activity in peripheral tissues (such as muscle and kidney) but does not affect SCOT activity in brain tissue. PSSI-51 reduces ketone body oxidation by inhibiting SCOT, thereby improving obesity-related hyperglycemia. PSSI-51 can be used in the study of type 2 diabetes (T2D) and has the potential to improve obesity-related metabolic disorders.

Phenylacetyl Coenzyme A (Phenylacetyl Coenzyme A) tetrasodium is an effector molecule of the TetR family transcriptional repressor PaaR. Phenylacetyl Coenzyme A tetrasodium changes the conformation of PaaR, causing it to dissociate from DNA and initiate transcription. Phenylacetyl Coenzyme A tetrasodium is promising for research of microbial metabolism.

Pentolinium tartrate is a ganglionic blocking agent. Pentolinium tartrate lowers blood pressure and permits regression of the signs and symptoms associated with severe hypertension.

L-Serine-S2-PEG-Formic acid is a linker for FGT-4.

Leptosin I is found in the strain of Leptosphaeria sp. OUPS-4. Leptosin I inhibits Leukemia lymphocyte P388 in culture with an ED50 of 1.13 μg/mL.

Laudexium methylsulfate is a neuromuscular blocking agent or skeletal muscle relaxant and a nondepolarizing neuromuscular blocking agent.

Larubrilstat is a vascular non-inflammatory molecule-1 (VNN1) inhibitor.

Laporolimus is an immunosuppressant.

Kibdelone C is a flavonoid compound found in Kibdelosporangium sp. with anticancer activity, exhibiting GI50 values of less than 1 nM against leukemia cell lines (SR) and renal cancer cell lines (SN12C). Kibdelone C is promising for anticancer research.

KB-208 is a phagocytosis inhibitor that improves immune thrombocytopenia (ITP) in mouse models at a dose of 1 mg/kg. KB-208 does not affect other blood parameters and does not elevate serum toxicity biomarkers. KB-208 can be used in immunology research.

Fenoxazoline is a decongestant and a vasoconstrictor.

FA-15 is an phenolic antioxidant. FA-15 has effect on stabilization of reactive fuels.

Ethyl 4-(butylamino)benzoate is an N-alkylated ester derivative of aminobenzoic acid.

DL-Theanine (DL-Glutamic acid γ-ethyl amide) is a natural compound showing tranquilizing effects in the brain.

Cumyl-chsinaca is a synthetic cannabinoid containing indazole-3-carboxamide

BPH-742 (compound 9) is a Geranylgeranyl diphosphate synthase inhibitor with IC50 of 0.1 μM. BPH-742 has antitumor activity.

BPH-628 is an aromatic geranylgeranyl diphosphate synthase (GGPPS) inhibitor, with a pIC50 of 6.1.

BCX-3607 is an orally active tissue factor/factor VIIa (TF-FVIIa) inhibitor (IC50: 4 nM). BCX-3607 blocks the extrinsic coagulation pathway by inhibiting the TF-FVIIa complex and significantly prolongs the prothrombin time (PT). BCX-3607 has a higher selectivity for TF-FVIIa than other serine proteases (such as thrombin, FXa, etc.). BCX-3607 can reduce thrombus weight and inflammatory response, and has both anti-thrombotic and anti-inflammatory effects. BCX-3607 can be used in the study of thrombosis-related diseases.

Amidepin is a new type of antiarrhythmic compound. Amidepin has the activity of regulating cardiac electrical activity. The main regulatory mechanism of amidepin involves ion channel or receptor interaction. Amidepin can be used for the study of arrhythmias.