PDGFP 1 is a promising probe for simultaneously differentiating glioma boundary and grades.

Piceid 6″-O-azelaic acid ester shows high intracellular tyrosinase inhibitory and depigmentating activities.

MEIS-IN-1 is a potent myeloid ecotropic viral integration site (MEIS) inhibitor to induce murine and human hematopoietic stem-cell expansion.

Kdn probe-1 is a fluorescent Kdn probe and reveals the localization of AfS in vesicles at the cell surface.

MEIS-IN-2 is a myeloid ecotropic viral integration site 1 (MEIS1) inhibitor.

MtDTBS-IN-1 is a particularly potent binder (KD = 57 nM) and inhibitor (Ki = 5 μM) of MtDTBS.

Quorum Sensing-IN-1 is a small-molecule quorum sensing inhibitor.

Transketolase-IN-1 is a promising herbicide candidate for weed control in wheat and maize fields targeting transketolase.

LtIA-F, a novel fluorescent analogue of LtIA, provides a wealth of pharmacological tools to explore the structure–function relationship, distribution, and ligand binding domain of the α3β2 nAChR subtype.

Nitro-coronene can be used to prepare near-infrared light-triggered lysosome-targetable carbon dots for photothermal therapy of cancer.

RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).

NCATS-SM4487 is a highly selective unique dihydropyrimidine inhibitor against GALK1, with an IC50 value of 0.05 μM.

NCATS- SM4487 is a highly selective unique dihydropyrimidine inhibitor against GALK1, with an IC50 value of 0.05 μM.

NI-Pano (CH-03) is a novel hypoxia-activated KDAC inhibitor. NI-Pano (CH-03) is reduced in an O2-dependent manner to release panobinostat.

PPO-IN-1 is a potent protoporphyrinogen IX oxidase (PPO) inhibitor with a Ki value of 2.5 nM.

Lynamicin B is a potential pesticide by acting as a lepidoptera-exclusive chitinase inhibitor with a Ki value of 8.76 μM.

ThrRS-IN-2 is a threonyl-tRNA synthetase (ThrRS) inhibitor with an IC50 value of 56.5 ± 3.5 μM.

N-Octylmaleimide is an alkylmaleimide, which can inhibit rat liver glucose 6-phosphatase.

Salpyran is a Cu(II) selective chelator with therapeutic potential.

PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.

Plasma kallikrein-IN-1 is a PKK inhibitor with an IC50 value of 0.5 nM.

MCA17-1 shows stronger bioactivity than the positive control obeticholic acid (OCA) against liver fibrosis.

Nln activator 1 is a first-in-class peptidomimetic neurolysin activator possessing enhanced brain penetration and stability.

RdRP-IN-3 is a promising anti-influenza drug candidate by inhibiting the activity of RNA-dependent RNA polymerase (RdRp).

Kbz probe 1 serves as a versatile probe for interrogating histone benzoylation and interactions in living cells.

Se-DMC attenuates complete Freund’s adjuvant (CFA)-induced inflammatory response, nociception, and neurobehavioral deficits in mice.

Spectinamide-1599 is a combination partner for anti-tuberculosis therapy.

Mycophenolate mofetil (RS 61443) hydrochloride is a immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPD) type I/II with IC50s of 39 nM and 27 nM, respectively.

PKM2-IN-3 is a inhibitor of PKM2 kinase with IC50 value of 4.1μM. PKM2-IN-3 exhibits an anti-neuroinflammatory effect by inhibiting PKM2-mediated glycolysis and NLRP3 activation.

Hyperectumine exhibits moderate anti-inflammatory activity via suppression of LPS-activated inflammatory mediators in RAW 264.7 macrophage cells.