Cat. No. | Product Name | Field of Application | Chemical Structure |
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A630 | Hanwha patent anti-VCAM-1 Biosimilar(Anti-VCAM1 / CD106 Reference Antibody) Featured |
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A629 | ELB-031 Biosimilar(Anti-TYRO3 Reference Antibody) Featured |
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A628 | INSERM patent anti-CO-029 Biosimilar(Anti-TSPAN8 Reference Antibody) Featured |
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A627 | Lilotomab Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured |
Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity.
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A626 | AGS-67E Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured |
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A625 | Otlertuzumab Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured |
Otlertuzumab (TRU-016) is a humanized anti-CD37 monoclonal antibody that can be used for cancer research.
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A624 | Naratuximab Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured |
Naratuximab (Anti-TSPAN26/CD37 Reference Antibody (naratuximab)) is a humanized monoclonal antibody that binds CD37 (TSPAN26). Naratuximab can be used to synthesize an ADC compound, Naratuximab emtansine.
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A623 | Schering patent anti-TSLP Biosimilar(Anti-TSLP Reference Antibody) Featured |
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A622 | K1-70 Biosimilar(Anti-TSHR Reference Antibody) Featured |
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A621 | Flanvotumab Biosimilar(Anti-TRP1 / TYRP1 Reference Antibody) Featured |
Flanvotumab (IMC-20D7S) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab acts function via natural killing-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Flanvotumab has potent anti-tumor activity and good tolerance.
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A620 | Sacituzumab Biosimilar(Anti-TROP2 Reference Antibody) Featured |
Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab is used for the synthesis of antibody-drug conjugates (ADC) drugs. Antibody-drug conjugates with sacituzumab (sacituzumab govitecan) (HY-132254) targeting TROP-2 have been approved for the field of triple-negative breast cancer.
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A619 | Sacituzumab govitecan Biosimilar(Anti-TROP2 Reference Antibody) Featured |
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity.
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A618 | Rinat patent anti-TrkB Biosimilar(Anti-TrkB / NTRK2 Reference Antibody) Featured |
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A616 | PY314 Biosimilar(Anti-TREM2 Reference Antibody) Featured |
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A615 | PY159 Biosimilar(Anti-TREM1 / CD354 Reference Antibody) Featured |
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A614 | Genentech patent anti-Tryptase Beta 1 Biosimilar(Anti-TPSAB1 Reference Antibody) Featured |
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A613 | Wyeth patent anti-5T4 Biosimilar(Anti-TPBG Reference Antibody) Featured |
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A612 | PF-06263507 Biosimilar(Anti-TPBG Reference Antibody) Featured |
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A611 | ASN004 Biosimilar(Anti-TPBG Reference Antibody) Featured |
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A610 | Naptumomab Biosimilar(Anti-TPBG Reference Antibody) Featured |
Naptumomab is a fusion protein of a tumor-targeting superantigen (TTS). Naptumomab stimulates the immune system to recognize and kill tumor cells and can be used in the study of refractory solid tumors such as renal cell carcinoma.
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A609 | Abbvie patent anti-TNFSF9 Biosimilar(Anti-TNFSF9 / 4-1BBL Reference Antibody) Featured |
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A608 | Cusatuzumab Biosimilar(Anti-TNFSF7 / CD27L / CD70 Reference Antibody) Featured |
Cusatuzumab is a human αCD70 monoclonal antibody. Cusatuzumab shows cytotoxicity activity with enhanced antibody-dependent cellular. Cusatuzumab reduces leukemia stem cells (LSCs) and triggers gene signatures related to myeloid differentiation and apoptosis. Cusatuzumab has the potential for the research of Acute myeloid leukemia (AML).
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A607 | Vorsetuzumab Biosimilar(Anti-TNFSF7 / CD27L / CD70 Reference Antibody) Featured |
Vorsetuzumab (Anti-Human CD70 Recombinant Antibody) is a human anti-CD70 antibody. Vorsetuzumab enhances macrophage-related phagocytosis of renal carcinoma cells, shows inhibitory efficacy against Burkitt’s lymphoma.
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A606 | Dapirolizumab Biosimilar(Anti-TNFSF5 / CD40L / CD154 Reference Antibody) Featured |
Dapirolizumab is a monoclonal antibodi against CD40 ligand. Dapirolizumab targets CD40L, blocks its interaction with CD40 receptors, and inhibits adaptive immune activation. Dapirolizumab attenuates systemic lupus erythematosus.
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A605 | Ruplizumab Biosimilar(Anti-TNFSF5 / CD40L / CD154 Reference Antibody) Featured |
Ruplizumab (BG 9588) is a humanized monoclonal anti-CD40L (TNF Receptor) IgG1κ antibody. Ruplizumab has the potential for systemic lupus erythematosus disease research.
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A604 | Amlitelimab Biosimilar(Anti-TNFSF4 / OX40L / CD252 Reference Antibody) Featured |
Amlitelimab () is an anti-OX40 Ligand (OX40L) monoclonal antibody (mAb). Amlitelimab inhibits OX40-OX40L interaction, and can be used in the research of atopic dermatitis.
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A603 | Oxelumab Biosimilar(Anti-TNFSF4 / OX40L / CD252 Reference Antibody) Featured |
Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma.
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DC8913 | Dabigatran etexilate mesylate Featured |
Dabigatran etexilate mesylate (BIBR 1048MS) serves as the orally bioavailable prodrug of the active anticoagulant dabigatran. Following absorption, this precursor compound undergoes enzymatic conversion to release dabigatran - a highly selective, reversible direct thrombin inhibitor (DTI) with exceptional potency (Ki = 4.5 nM).
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DC1010 | BIBR-1048 (Dabigatran etexilate) Featured |
BIBR-1048 (Dabigatran) represents a breakthrough in anticoagulant therapy as a potent, selective direct thrombin inhibitor.
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DC11003 | BL5923 Featured |
BL5923 (BL-5923) is a potent, highly specific, orally available inhibitor of CCR1 with IC50 of 20.4 and 22.8 nM for human and mouse CCR1, resepctively.
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