Negative control for PPTN

Less active enantiomer of LGH447, acting as a selective weak pan-PIM inhibitor (IC 50 (µM): PIM1 0.095; PIM2 0.522; PIM3 0.369) in comparision with LGH447 (IC 50 (µM): PIM1 0.001; PIM2 0.002; PIM3 0.002)

Deuterated internal standard for PhIP

Negative control for PFI-6

Negative control for PFI-653

Metabolite of PF-04691502, a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR

Pro-drug of furamidine, acting as antiprotozoal/antifungal agent

Novel PA-9 analog, acting as an antagonist of the PAC1 receptor, showing improved antagonistic activities than PA-9

Prodrug of antitumor agent oncrasin-72, with improved stability, pharmacokinetics, and safety

Novel potent and highly selective KDM1A chemoprobe, exhibiting a selectivity profile similar to the parent compound ORY-1001

PET Precursor of VU0467485

Negative control for NVS-MLLT-1

Nagative control for NVS-BPTF-1

Prodrug of NUC013, a novel DNA methytransferase inhibitor

Negative control for Homer

The negative control compound for ML323

Novel Highly Selective Inhibitor of Methyltransferase DOT1L, being more metabolically stable and significantly less toxic in vivo than pinometostat

Novel potent antitubercular agent, inhibiting decaprenylphosphoryl-β-d-ribose 2'-oxidase (DprE1), displaying better aqueous solubility and metabolic stability than PBTZ169

Negative control for MDC-4381

Negative control for MS4322

Negative control for MS154

Prodrug of MRS4738, dramatically reducing lung inflammation in a mouse asthma model

Negative control for MRK-740

Negative control for MLi-2

Negative control for MF-094

TH10785 is a small-molecule activator that binds to the active site of 8-oxo guanine DNA glycosylase 1 (OGG1) and enables the protein to completely cleave the damaged DNA strand, which results in an overall increased repair of oxidative DNA damage.

NCDM-32B is a novel potent and selective KDM4 inhibitor, impairing viability and transforming phenotypes of basal breast cancer.

Iclepertin (BI-425809) is a potent, selective and orally active glycine transporter 1 (GlyT1) inhibitor. Iclepertin is inactive against GlyT2. Iclepertin can be used for Alzheimer disease and schizophrenia research.

Tryptolinamide (TLAM) is a small-molecule compound that activates mitochondrial respiration in cybrids generated from patient-derived mitochondria and fibroblasts from patient-derived iPSCs, inhibits phosphofructokinase-1 (PFK1) with an ATP-uncompetitive