Novel selective and reversible LSD1 inhibitor (IC50 value of 60 nM), exhibiting the antiproliferative activity against HTB5, HTB3, HT1376, and HTB1 cells with IC50 values of 1.87, 0.18, 0.09, and 0.93 μM, respectively

The first small molecule antagonist of LRH-1 activity.

Novel potent agonist of the liver receptor homolog-1 (LRH-1, NR5A2)

Novel agonist of liver receptor homolog-1 (LRH-1), reducing the expression of lipogenic genes in mouse liver, and inflammation and disease severity in a mouse model of ulcerative colitis

Novel potent and specific inhibitor of O-linked β-N-acetylglucosamine transferase (OGT)

Novel p53 activator through the inhibition of MDM2

Novel LPA 1-3 agonist, inducing a calcium response in hLPA 1-3 cells within a range of 0.4 to 1.5-log lower potency, as compared to LPA

Novel LPA 1-3 agonist, inducing a calcium response in hLPA 1-3 cells within a range of 0.4 to 1.5-log lower potency, as compared to LPA

Novel inhibitor of both renal SGLT1 and SGLT2

Novel potent and selective peripheral AAK1 inhibitor

Potent antimitotic and oral tubulin binding agent, significantly inhibiting growth of a human non-small-cell lung tumor

Potent ligand of the 5-HT7 receptor

Novel LOX-activity sensor for cross-linking with a collagen peptide to chemoselectively target endogenous aldehydes generated by LOX

Lopinavir Secondary Metabolite

Opioid receptor agonist, acting on the µ-opioid receptors in the myenteric plexus of the large intestine

Natural neurotrophic agent

Antibiotic for treatment of bacterial infections including bronchitis and urinary tract infections, prevent urinary tract infections prior to surgery

Inhibitor of the Vesicular_monoamine_transporter_2>vesicular monoamine transporter-2 (VMAT2)

Novel potent and specific agonist of I 1 imidazoline receptors

Potent and selective ligand of imidazoline 1 receptor (I 1 R)

Novel Two-in-One Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites

Novel highly selective inhibitor of the low-molecular-weight protein tyrosine phosphatase (LMPTP), being highly orally bioavailable and reversing obesity-induced diabetes in mice

Novel AI-2 quorum-sensing inhibitor, affecting the starvation response and reducing virulence in several Vibrio species, most likely by interfering with LuxPQ

Novel p75NTR antagonist

Novel Probe for Imaging Tau Pathology in Transgenic Mouse and Rat Models

Negative control for LM11A-24

Novel Modulator of p75NTR-dependent motor neuron death

Novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2)

Novel inducer of biofilm dispersal, having a slower rate of NO release

Highly